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来自刺胞水母的生物活性毒素。

Bioactive toxins from stinging jellyfish.

作者信息

Badré Sophie

机构信息

Prevor, Moulin de Verville, 95760 Valmondois, France.

出版信息

Toxicon. 2014 Dec;91:114-25. doi: 10.1016/j.toxicon.2014.09.010. Epub 2014 Oct 5.

DOI:10.1016/j.toxicon.2014.09.010
PMID:25286397
Abstract

Jellyfish blooms occur throughout the world. Human contact with a jellyfish induces a local reaction of the skin, which can be painful and leave scaring. Systemic symptoms are also observed and contact with some species is lethal. A number of studies have evaluated the in vitro biological activity of whole jellyfish venom or of purified fractions. Hemolytic, cytotoxic, neurotoxic or enzymatic activities are commonly observed. Some toxins have been purified and characterized. A family of pore forming toxins specific to Medusozoans has been identified. There remains a need for detailed characterization of jellyfish toxins to fully understand the symptoms observed in vivo.

摘要

水母大量繁殖在世界各地都有发生。人类接触水母会引发皮肤局部反应,这种反应可能会很疼痛并留下疤痕。还会观察到全身症状,与某些水母物种接触甚至会致命。许多研究评估了完整水母毒液或纯化组分的体外生物活性。通常会观察到溶血、细胞毒性、神经毒性或酶活性。一些毒素已被纯化并鉴定。已经鉴定出一类特定于水母纲动物的成孔毒素家族。仍需要对水母毒素进行详细表征,以充分了解在体内观察到的症状。

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