Ostermann J, Horwich A L, Neupert W, Hartl F U
Institut für Physiologische Chemie der Universität München, FRG.
Nature. 1989 Sep 14;341(6238):125-30. doi: 10.1038/341125a0.
Mitochondrial heat-shock protein hsp60 functions in the folding of proteins imported into mitochondria. Folding occurs at the surface of hsp60 in an ATP-mediated reaction, followed by release of the bound polypeptides. We propose that hsp60 catalyses protein folding.