Suojanen Juho, Färkkilä Esa, Helkamaa Tessa, Loimu Venla, Törnwall Jyrki, Lindqvist Christian, Hagström Jaana, Mesimäki Karri
Department of Oral and Maxillofacial Diseases, Helsinki University Central Hospital, Helsinki FIN-00014, Finland.
Department of Oncology, Helsinki University Central Hospital, Helsinki FIN-00014, Finland.
Oncol Lett. 2014 Nov;8(5):2175-2178. doi: 10.3892/ol.2014.2505. Epub 2014 Sep 5.
Renal cell carcinomas (RCCs) have a tendency to metastasize at an early stage, therefore, the patients frequently exhibit metastatic disease at the time of diagnosis. Common locations for the metastases are adjacent organs and abdominal lymph nodes; however, occasionally metastasis to the peripheral organs may be the initial clinical symptom. The 71-year-old male patient in the current case suffered from radioresistant and aggressively behaving RCC metastasis in the mandible and lower lip, which was successfully managed by surgical resection. RCC metastasis to the facial area is considered to be uncommon based on a review of the existing literature. RCC are somewhat radioresistant and therefore, palliative surgery must be considered when treating patients with this metastatic disease.
肾细胞癌(RCC)有早期转移的倾向,因此,患者在诊断时常常已出现转移性疾病。转移的常见部位是邻近器官和腹部淋巴结;然而,偶尔转移至外周器官可能是最初的临床症状。本病例中的71岁男性患者患有对放疗耐药且侵袭性生长的下颌骨和下唇肾细胞癌转移灶,通过手术切除成功治愈。根据现有文献回顾,肾细胞癌转移至面部区域被认为不常见。肾细胞癌对放疗 somewhat 耐药,因此,在治疗这种转移性疾病的患者时必须考虑姑息性手术。 (注:原文中“somewhat”翻译为“ somewhat”是因为不太明确其确切意思,可能是“有点”之类的含义,需结合更多语境准确理解。)