Ghaouti Merieme, Roquet Laurence, Baron Maximilien, Pfister Christian, Sabourin Jean-Christophe
Department of Cytopathology, Charles-Nicole Hospital, Rouen University Hospital, Rouen, France.
Diagn Pathol. 2014 Oct 8;9:186. doi: 10.1186/s13000-014-0186-8.
Thyroid-like follicular carcinoma of the kidney is an extremely rare histological variant of renal cell carcinoma. It was described only recently and is not included in the World Health Organization classification of renal tumors. This tumor characteristically shows similar histology to thyroid follicular carcinoma but lacks typical thyroid markers. Herein, we report a new case of thyroid-like follicular carcinoma of the kidney diagnosed in a partial nephrectomy specimen in a 68-year-old-woman. We present typical histological and immunohistochemical findings, discuss differential diagnosis and provide a review of the literature.Virtual Slides: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/13000_2014_186.
肾甲状腺样滤泡癌是肾细胞癌一种极其罕见的组织学变体。它直到最近才被描述,未被纳入世界卫生组织肾肿瘤分类中。该肿瘤特征性地表现出与甲状腺滤泡癌相似的组织学特征,但缺乏典型的甲状腺标志物。在此,我们报告一例在一名68岁女性的部分肾切除标本中诊断出的肾甲状腺样滤泡癌新病例。我们展示了典型的组织学和免疫组化结果,讨论了鉴别诊断并提供了文献综述。虚拟切片:本文的虚拟切片可在此处找到:http://www.diagnosticpathology.diagnomx.eu/vs/13000_2014_186 。