Pérez Ramírez Sara, Parra Verónica, Avilés Izquierdo José Antonio, Vicario José Luis, Martín Miguel, Márquez-Rodas Iván
Tumori. 2014 Jul-Aug;100(4):144e-7e. doi: 10.1700/1636.17932.
Spontaneous regressions of metastatic melanoma are rare, but several cases have been described in the literature. Although the mechanism of the phenomenon is not well understood, it is postulated that an activation of the immune system is behind it. Here we report the case of a patient with metastatic melanoma that, without any treatment, regressed spontaneously. The patient presented psoriasis (a disease of the skin related with autoimmunity) linked with HLA-Cw6. We review the literature and hypothesize with the possible relationship between psoriasis, HLA-Cw6 and the spontaneous regression.
转移性黑色素瘤的自发消退很罕见，但文献中已有数例相关报道。尽管该现象的机制尚不完全清楚，但据推测其背后是免疫系统的激活。在此，我们报告一例转移性黑色素瘤患者未经任何治疗而自发消退的病例。该患者患有与自身免疫相关的银屑病（一种皮肤疾病），且与HLA - Cw6相关。我们回顾了文献，并对银屑病、HLA - Cw6与自发消退之间可能的关系进行了推测。
