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化妆品中使用的葡萄(葡萄属)衍生成分的安全性评估。

Safety assessment of Vitis vinifera (grape)-derived ingredients as used in cosmetics.

作者信息

Fiume Monice M, Bergfeld Wilma F, Belsito Donald V, Hill Ronald A, Klaassen Curtis D, Liebler Daniel C, Marks James G, Shank Ronald C, Slaga Thomas J, Snyder Paul W, Andersen F Alan

机构信息

Cosmetic Ingredient Review Senior Scientific Analyst/Writer, Washington, DC, USA.

Cosmetic Ingredient Review Expert Panel Member, Washington, DC, USA.

出版信息

Int J Toxicol. 2014 Sep-Oct;33(3 Suppl):48S-83S. doi: 10.1177/1091581814545247.

Abstract

The Cosmetic Ingredient Review Expert Panel (Panel) assessed the safety of 24 Vitis vinifera (grape)-derived ingredients and found them safe in the present practices of use and concentration in cosmetics. These ingredients function in cosmetics mostly as skin-conditioning agents, but some function as antioxidants, flavoring agents, and/or colorants. The Panel reviewed the available animal and clinical data to determine the safety of these ingredients. Additionally, some constituents of grapes have been assessed previously for safety as cosmetic ingredients by the Panel, and others are compounds that have been discussed in previous Panel safety assessments.

摘要

化妆品成分审查专家小组评估了24种葡萄(葡萄属)衍生成分的安全性,发现它们在化妆品目前的使用方法和浓度下是安全的。这些成分在化妆品中主要起皮肤调理剂的作用,但有些还起抗氧化剂、调味剂和/或着色剂的作用。该小组审查了现有的动物和临床数据,以确定这些成分的安全性。此外,葡萄的一些成分此前已由该小组评估其作为化妆品成分的安全性,其他一些成分则是该小组此前安全评估中讨论过的化合物。

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