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[茶碱在淋巴细胞培养中的免疫调节特性研究]

[Study of the immunotropic properties of theophylline in lymphocyte culture].

作者信息

Sokolov E I, Glan P V, Sashkina T I

出版信息

Farmakol Toksikol. 1989 Jul-Aug;52(4):67-70.

PMID:2530107
Abstract

The effect of theophylline on the activation of suppressor cells by histamine was studied in the experiments with mononuclear cells of blood of patients with bronchial asthma and healthy donors. Theophylline (1-5 micrograms/ml) was shown to be able of activating suppressed function of cells of the patients. Incubation of mononuclear cells of the healthy donors with theophylline did not change the process of suppressor formation in vitro.

摘要

在对支气管哮喘患者和健康供体的血液单核细胞进行的实验中,研究了茶碱对组胺激活抑制细胞的作用。已表明茶碱(1 - 5微克/毫升)能够激活患者细胞的抑制功能。健康供体的单核细胞与茶碱一起孵育,在体外并未改变抑制细胞的形成过程。

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