• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

使用局部振动标记 (LOVIT) 进行深层临床光声成像的杂波消除。

Clutter elimination for deep clinical optoacoustic imaging using localised vibration tagging (LOVIT).

机构信息

Institute of Applied Physics, University of Bern, Sidlerstrasse 5, 3012 Bern, Switzerland ; Joint Department of Physics, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey SM2 5PT, UK ; CRUK-EPSRC Cancer Imaging Centre, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey SM2 5PT, UK.

Joint Department of Physics, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey SM2 5PT, UK ; CRUK-EPSRC Cancer Imaging Centre, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey SM2 5PT, UK.

出版信息

Photoacoustics. 2013 Aug 2;1(2):19-29. doi: 10.1016/j.pacs.2013.07.002. eCollection 2013 May.

DOI:10.1016/j.pacs.2013.07.002
PMID:25302147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4134903/
Abstract

This paper investigates a novel method which allows clutter elimination in deep optoacoustic imaging. Clutter significantly limits imaging depth in clinical optoacoustic imaging, when irradiation optics and ultrasound detector are integrated in a handheld probe for flexible imaging of the human body. Strong optoacoustic transients generated at the irradiation site obscure weak signals from deep inside the tissue, either directly by propagating towards the probe, or via acoustic scattering. In this study we demonstrate that signals of interest can be distinguished from clutter by tagging them at the place of origin with localised tissue vibration induced by the acoustic radiation force in a focused ultrasonic beam. We show phantom results where this technique allowed almost full clutter elimination and thus strongly improved contrast for deep imaging. Localised vibration tagging by means of acoustic radiation force is especially promising for integration into ultrasound systems that already have implemented radiation force elastography.

摘要

本文研究了一种新方法，可用于消除深层光声成像中的杂波。当将辐射光学和超声探测器集成在手持式探头中，以灵活地对人体进行成像时，杂波会极大地限制临床光声成像的深度。在辐射部位产生的强光声瞬变会通过向探头传播，或通过声散射，直接掩盖来自组织深部的弱信号。在这项研究中，我们证明通过在聚焦超声束中利用声辐射力在起源处引起局部组织振动，可以将感兴趣的信号与杂波区分开来。我们展示了幻影结果，其中该技术几乎完全消除了杂波，从而大大提高了深层成像的对比度。通过声辐射力进行局部振动标记对于集成到已经实现辐射力弹性成像的超声系统中尤其有前途。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/7513951c9036/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/fc5e5d2f46fe/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/2e7b5a2f4472/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/f38a933bc6b7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/0172968c90ff/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/72541bea87fc/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/c73c52225988/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/7b9484472dff/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/9f5691a9bb79/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/7513951c9036/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/fc5e5d2f46fe/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/2e7b5a2f4472/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/f38a933bc6b7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/0172968c90ff/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/72541bea87fc/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/c73c52225988/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/7b9484472dff/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/9f5691a9bb79/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e190/4134903/7513951c9036/gr9.jpg

相似文献

1
Clutter elimination for deep clinical optoacoustic imaging using localised vibration tagging (LOVIT).使用局部振动标记 (LOVIT) 进行深层临床光声成像的杂波消除。
Photoacoustics. 2013 Aug 2;1(2):19-29. doi: 10.1016/j.pacs.2013.07.002. eCollection 2013 May.
2
Rapid scanning wide-field clutter elimination in epi-optoacoustic imaging using comb LOVIT.在落射光声成像中使用梳状 LOVIT 进行快速扫描宽场杂波消除
Photoacoustics. 2018 Feb 19;10:20-30. doi: 10.1016/j.pacs.2018.02.001. eCollection 2018 Jun.
3
Effect of irradiation distance on image contrast in epi-optoacoustic imaging of human volunteers.照射距离对人体志愿者表面光声成像中图像对比度的影响。
Biomed Opt Express. 2014 Oct 1;5(11):3765-80. doi: 10.1364/BOE.5.003765. eCollection 2014 Nov 1.
4
Deformation-compensated averaging for clutter reduction in epiphotoacoustic imaging in vivo.体内光声成像中的杂波减少的变形补偿平均法。
J Biomed Opt. 2012 Jun;17(6):066007. doi: 10.1117/1.JBO.17.6.066007.
5
Image processing improvements afford second-generation handheld optoacoustic imaging of breast cancer patients.图像处理方面的改进实现了对乳腺癌患者的第二代手持式光声成像。
Photoacoustics. 2022 Mar 2;26:100343. doi: 10.1016/j.pacs.2022.100343. eCollection 2022 Jun.
6
Large-field-of-view optical-resolution optoacoustic microscopy using a stationary silicon-photonics acoustic detector.采用静态硅光子学声学探测器的大视场光分辨率光声显微镜。
J Biomed Opt. 2024 Jan;29(Suppl 1):S11511. doi: 10.1117/1.JBO.29.S1.S11511. Epub 2024 Jan 5.
7
Probe Oscillation Shear Elastography (PROSE): A High Frame-Rate Method for Two-Dimensional Ultrasound Shear Wave Elastography.探头振荡剪切弹性成像（PROSE）：一种用于二维超声剪切波弹性成像的高帧率方法。
IEEE Trans Med Imaging. 2016 Sep;35(9):2098-106. doi: 10.1109/TMI.2016.2550007. Epub 2016 Apr 4.
8
All-optical optoacoustic microscopy based on probe beam deflection technique.基于探测光束偏转技术的全光学光声显微镜。
Photoacoustics. 2016 Feb 24;4(3):91-101. doi: 10.1016/j.pacs.2016.02.001. eCollection 2016 Sep.
9
Imaging and characterizing shear wave and shear modulus under orthogonal acoustic radiation force excitation using OCT Doppler variance method.使用光学相干断层扫描（OCT）多普勒方差法在正交声辐射力激发下对剪切波和剪切模量进行成像与表征。
Opt Lett. 2015 May 1;40(9):2099-102. doi: 10.1364/OL.40.002099.
10
Downgrading and Upgrading Gray-Scale Ultrasound BI-RADS Categories of Benign and Malignant Masses With Optoacoustics: A Pilot Study.超声 BI-RADS 灰阶良恶性肿块降级与升级与光声成像：一项初步研究。
AJR Am J Roentgenol. 2018 Sep;211(3):689-700. doi: 10.2214/AJR.17.18436. Epub 2018 Jul 5.

引用本文的文献

1
Phantoms for evaluating the impact of skin pigmentation on photoacoustic imaging and oximetry performance.用于评估皮肤色素沉着对光声成像和血氧测定性能影响的体模。
Biomed Opt Express. 2023 Oct 12;14(11):5735-5748. doi: 10.1364/BOE.501950. eCollection 2023 Nov 1.
2
Photoacoustic imaging on its way toward clinical utility: a tutorial review focusing on practical application in medicine.光声成象迈向临床应用：聚焦于医学实际应用的教程综述
J Biomed Opt. 2023 Dec;28(12):121205. doi: 10.1117/1.JBO.28.12.121205. Epub 2023 Jun 8.
3
Performance evaluation of mesoscopic photoacoustic imaging.

本文引用的文献

1
Real time tissue elasticity imaging using the combined autocorrelation method.使用联合自相关方法的实时组织弹性成像
J Med Ultrason (2001). 2002 Sep;29(3):119-28. doi: 10.1007/BF02481234.
2
EFSUMB guidelines and recommendations on the clinical use of ultrasound elastography. Part 1: Basic principles and technology.EFSUMB 关于超声弹性成像临床应用的指南与建议。第 1 部分：基本原理与技术。
Ultraschall Med. 2013 Apr;34(2):169-84. doi: 10.1055/s-0033-1335205. Epub 2013 Apr 4.
3
Deformation-compensated averaging for clutter reduction in epiphotoacoustic imaging in vivo.
介观光声成像的性能评估
Photoacoustics. 2023 May 6;31:100505. doi: 10.1016/j.pacs.2023.100505. eCollection 2023 Jun.
4
LED-based photoacoustic imaging for preoperative visualization of lymphatic vessels in patients with secondary limb lymphedema.基于发光二极管的光声成像用于继发性肢体淋巴水肿患者术前淋巴管可视化
Photoacoustics. 2022 Dec 28;29:100446. doi: 10.1016/j.pacs.2022.100446. eCollection 2023 Feb.
5
Photoacoustic imaging phantoms for assessment of object detectability and boundary buildup artifacts.用于评估目标可检测性和边界增强伪像的光声成像体模。
Photoacoustics. 2022 Mar 21;26:100348. doi: 10.1016/j.pacs.2022.100348. eCollection 2022 Jun.
6
Suppression of acoustic reflection artifact in endoscopic photoacoustic tomographic images based on approximation of ideal signals.基于理想信号逼近的内窥光声层析成像图像中声学反射伪像的抑制。
Technol Health Care. 2022;30(S1):201-214. doi: 10.3233/THC-228019.
7
Review of consensus test methods in medical imaging and current practices in photoacoustic image quality assessment.医学成像中一致性测试方法的综述及光声图像质量评估的现行实践。
J Biomed Opt. 2021 Sep;26(9). doi: 10.1117/1.JBO.26.9.090901.
8
Real-time interleaved spectroscopic photoacoustic and ultrasound (PAUS) scanning with simultaneous fluence compensation and motion correction.实时交错光谱光声和超声（PAUS）扫描，具有同时的剂量补偿和运动校正。
Nat Commun. 2021 Jan 29;12(1):716. doi: 10.1038/s41467-021-20947-5.
9
Feasibility of identifying reflection artifacts in photoacoustic imaging using two-wavelength excitation.利用双波长激发在光声成像中识别反射伪像的可行性。
Biomed Opt Express. 2020 Sep 22;11(10):5745-5759. doi: 10.1364/BOE.401375. eCollection 2020 Oct 1.
10
Photoacoustic imaging for surgical guidance: Principles, applications, and outlook.用于手术引导的光声成像：原理、应用及展望。
J Appl Phys. 2020 Aug 14;128(6):060904. doi: 10.1063/5.0018190. Epub 2020 Aug 13.
体内光声成像中的杂波减少的变形补偿平均法。
J Biomed Opt. 2012 Jun;17(6):066007. doi: 10.1117/1.JBO.17.6.066007.
4
Optical coherence tomography.光学相干断层扫描。
J Microsc. 2012 Sep;247(3):209-19. doi: 10.1111/j.1365-2818.2012.03619.x. Epub 2012 Jun 18.
5
Improved contrast deep optoacoustic imaging using displacement-compensated averaging: breast tumour phantom studies.利用位移补偿平均提高对比度的深层光声成像：乳腺肿瘤体模研究。
Phys Med Biol. 2011 Sep 21;56(18):5889-901. doi: 10.1088/0031-9155/56/18/008. Epub 2011 Aug 18.
6
Label-free oxygen-metabolic photoacoustic microscopy in vivo.无标记氧代谢光声显微镜活体成像。
J Biomed Opt. 2011 Jul;16(7):076003. doi: 10.1117/1.3594786.
7
Multiplex photoacoustic molecular imaging using targeted silica-coated gold nanorods.使用靶向二氧化硅包覆金纳米棒的多重光声分子成像。
Biomed Opt Express. 2011 Jul 1;2(7):1828-35. doi: 10.1364/BOE.2.001828. Epub 2011 Jun 2.
8
3-D photoacoustic and pulse echo imaging of prostate tumor progression in the mouse window chamber.3-D 光声和脉冲回波成像在小鼠窗室中检测前列腺肿瘤的进展。
J Biomed Opt. 2011 Feb;16(2):026012. doi: 10.1117/1.3540668.
9
Gelatin-agar lumbosacral spine phantom: a simple model for learning the basic skills required to perform real-time sonographically guided central neuraxial blocks.明胶-琼脂腰骶椎模型：一种用于学习进行实时超声引导下中枢神经轴索阻滞所需基本技能的简单模型。
J Ultrasound Med. 2011 Feb;30(2):263-72. doi: 10.7863/jum.2011.30.2.263.
10
Breast lesions: quantitative elastography with supersonic shear imaging--preliminary results.乳腺病变：超声剪切波弹性成像的定量研究——初步结果。
Radiology. 2010 Jul;256(1):297-303. doi: 10.1148/radiol.10090385. Epub 2010 May 26.