Kölmel H W, Sudau C
Department of Neurology, Klinikum Rudolf-Virchow, Standort Charlottenburg, Berlin.
J Neurol. 1989 Oct;236(7):424-6. doi: 10.1007/BF00314904.
The cell count and the helper/inducer to suppressor/cytotoxic T-cell ratio (T4:T8) in cerebrospinal fluid (CSF) were compared in patients with multiple sclerosis (MS) and other neurological diseases. The T4:T8 ratio was higher in patients with MS than in patients with other neurological diseases. A low or normal CSF cell count was associated with a more significant increase in the T4:T8 ratio in patients with MS. These findings imply that the increased T4:T8 ratio found in MS is masked by an inflammatory pleocytosis or that the shift appears only when pleocytosis is absent.
对患有多发性硬化症（MS）的患者和患有其他神经疾病的患者的脑脊液（CSF）中的细胞计数以及辅助/诱导型T细胞与抑制/细胞毒性T细胞的比例（T4:T8）进行了比较。MS患者的T4:T8比例高于其他神经疾病患者。脑脊液细胞计数低或正常与MS患者T4:T8比例的更显著升高相关。这些发现表明，MS中发现的T4:T8比例升高被炎症性细胞增多所掩盖，或者这种变化仅在没有细胞增多时出现。
