El Haj Mohamad, Caillaud Marie, Verny Christophe, Fasotti Luciano, Allain Philippe
Research Unit on Cognitive and Affective Sciences, Department of Psychology, University of North of France, Lille, France.
UNAM University, Psychology Laboratory (EA 4638), University of Nantes and Angers, France.
J Neuropsychol. 2016 Mar;10(1):77-89. doi: 10.1111/jnp.12057. Epub 2014 Oct 10.
Destination memory refers to the recall of the destination of previously relayed information, and source memory refers to the recollection of the origin of received information. We compared both memory systems in Huntington's disease (HD) participants. For this, HD participants and healthy adults had to put 12 items in a black or a white box (destination task), and to extract another 12 items from a blue or a red box (source task). Afterwards, they had to decide in which box each item had previously been deposited (destination memory), and from which box each item had previously been extracted (source memory). HD participants showed poorer source as well as destination recall performance than healthy adults in the proposed tasks. Correlation analysis showed that destination recall was significantly correlated with episodic recall in HD participants. Destination memory impairment in HD participants seems to be considerably influenced by their episodic memory performance.
目的记忆是指对先前传递信息的目的地的回忆，而来源记忆是指对接收到信息的来源的回忆。我们比较了亨廷顿舞蹈症（HD）患者的这两种记忆系统。为此，HD患者和健康成年人必须将12个物品放入黑色或白色盒子中（目的任务），并从蓝色或红色盒子中取出另外12个物品（来源任务）。之后，他们必须决定每个物品先前被放置在哪个盒子中（目的记忆），以及每个物品先前是从哪个盒子中取出的（来源记忆）。在所提出的任务中，HD患者表现出比健康成年人更差的来源及目的回忆表现。相关性分析表明，HD患者的目的回忆与情景回忆显著相关。HD患者的目的记忆损害似乎受到其情景记忆表现的显著影响。
