Rezende Ederlon, Ferez Marcus Antonio, Silva Junior João Manoel da, Oliveira Amanda Maria Ribas Rosa de, Viana Renata Andréa Pietro Pereira, Mendes Ciro Leite, Toledo Diogo de Oliveira, Ribeiro Neto Miguel Costa, Setoyama Tatiane Akemi
Hospital do Servidor Público Estadual Francisco Morato de Oliveira, São Paulo, SP, Brasil.
Hospital São Francisco, Ribeirão Preto, SP, Brasil.
Rev Bras Ter Intensiva. 2010 Mar;22(1):5-10.
Anemia is common in severely ill patients, and blood sampling plays a relevant causative role. Consequently, blood transfusions are frequent an related to several complications. Trying to reduce the transfusion-related risk, minimizing blood loss is mandatory. Thus, this work aimed to evaluate a closed blood sampling system as a strategy to spare unnecessary blood losses and transfusions.
This was a prospective, randomized, controlled, multicenter, 6 months, clinical trial. The patients were assigned to either VAMP (Venous Arterial Blood Management Protection) group, using a closed blood sampling system, or control group. The groups' transfusion rate, as well as hemoglobin (Hb) and Hematocrit (Ht) changes were compared for 14 days.
Were included 127 patients, 65 assigned to the control group, and 62 to VAMP. During the intensive care unit stay, both groups experienced both hemoglobin and hematocrit drops. However, when the final Ht and Hb were compared between the groups, a difference was identified with higher values in the VAMP group (p=0.03; p=0.006, respectively). No statistical difference was found for both groups transfusion rates, although the VAMP group had an absolute 12% blood transfusion reduction.
The use of a closed blood sampling system was able to minimize blood count values changes, however failed to reduce transfusions rate.