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[巴登-符腾堡州假膜性喉炎横断面研究显示的室外污染所致健康风险的意义]

[The significance of health risks caused by outdoor pollution, demonstrated by cross-sectional studies of pseudocroup in Baden-Württemberg].

作者信息

Wichmann H E, Hübner H R, Malin E, Köhler B, Hippke G, Fischer D, Bontemps M, Huenges R, Rebmann H, Walzer H

出版信息

Offentl Gesundheitswes. 1989 Aug-Sep;51(8-9):414-20.

PMID:2531323
Abstract

In the FRG the question of health effects by ambient (outdoor) air pollution is often considered with respect to respiratory diseases in children, especially group syndrome. Therefore, the results of a cross-sectional study in Baden-Württemberg are discussed as an example for the role of "outdoor pollution" at presently observed concentrations. In the study that was performed in Stuttgart, Tübingen/Reutlingen and Freudenstadt, the parents of 8.420 children at the age of 6 years participated (response rate 93%). Their reports on diseases were additionally validated and completed by the paediatricians concerned. The "crude" prevalence for the age group 0-6 years is about 9% each for croup syndrome and obstructive bronchitis. This is strongly influenced by sex, disposition in the family, education and nationality of the parents. In contrast, influences of ambient air pollution are less clear or missing. Pollution measurements on a sufficient spatial scale were only available for Stuttgart, where logistic regression showed after adjustment for the relevant confounders only that croup syndrome was slightly increased in streets with high traffic load. For childhood asthma (prevalence 1.5%) a correlation with traffic-dependent pollutants (NO2, NO, CO) and traffic load is found. These results are compared with those from North Rhine Westphalia, and their limitations are discussed.

摘要

在联邦德国,环境(室外)空气污染对健康的影响问题常常与儿童的呼吸道疾病相关联,尤其是群体综合征。因此,以巴登-符腾堡州的一项横断面研究结果为例,探讨当前观测浓度下“室外污染”所起的作用。在斯图加特、图宾根/罗伊特林根和弗罗伊登施塔特开展的这项研究中,8420名6岁儿童的家长参与其中(回应率为93%)。他们关于疾病的报告还经过了相关儿科医生的进一步验证和完善。0至6岁年龄组中哮吼综合征和阻塞性支气管炎的“粗略”患病率均约为9%。这受到性别、家庭遗传因素、父母的教育程度和国籍的强烈影响。相比之下,环境空气污染的影响则不太明确或并不存在。仅在斯图加特获得了足够空间尺度上的污染测量数据,在对相关混杂因素进行调整后,逻辑回归显示,在交通流量大的街道上,哮吼综合征的发病率略有上升。对于儿童哮喘(患病率为1.5%),发现其与交通相关污染物(二氧化氮、一氧化氮、一氧化碳)及交通流量存在关联。将这些结果与北莱茵-威斯特法伦州的结果进行了比较,并讨论了其局限性。

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