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地中海饮食在2型糖尿病预防和管理中的作用。

Role of Mediterranean diet in prevention and management of type 2 diabetes.

作者信息

Khemayanto Hidayat, Shi Bimin

机构信息

Department of Endocrinology & Metabolism, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215000, China.

Department of Endocrinology & Metabolism, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215000, China. Email:

出版信息

Chin Med J (Engl). 2014;127(20):3651-6.

Abstract

OBJECTIVE

To summarize the importance of Mediterranean diet in the prevention and management of type 2 diabetes.

DATA SOURCES

We searched electronic database on PubMed up to 14 April 2014, we identified these articles with following key words: "Mediterranean diet" and "diabetes". The initial search resulted in 451 entries. The search strategy had no language and publication date restrictions. The relevance of the studies was assessed based only on the title and abstract. The studies included in our review had to match the following inclusion criteria: (1) randomized clinical trials and meta-analysis or systematic review, and (2) provided strong evidence for the diet as a way to prevent type 2 diabetes, and improve glycemic control and cardiovascular risk factors in diabetic patients. We reviewed 49 manuscripts and only 22 met our inclusion criteria.

STUDY SELECTION

Relevant literatures including randomized control trials, meta-analysis or systematic review.

RESULTS

Based on several studies, Mediterranean diet is inversely related to type 2 diabetes and plays important roles in the management of type 2 diabetes. Based on the evidence gathered and evaluated from various studies, we concluded combination and interaction of Mediterranean diet components, such as fruits, vegetables, nuts, legumes, whole grains, fish and moderate intakes of red wine, which contain essential nutrients and health promoting properties, including high fibers, high magnesium, high anti-oxidant and high monounsaturatal fatty acids (MUFA). Interaction and combination of these essential nutrients and health promoting properties found to lower body weight, hemoglobin A1C (HbA1c), low density lipoprotein (LDL), oxidative-stress and improve high density lipoprotein (HDL) level; which are beneficial for prevention and prognosis improvement of type 2 diabetes.

CONCLUSIONS

In the modern society, poor dietary habits accompanied by inadequate physical activity are associated with the risk of having obesity and type 2 diabetes. Promoting healthy lifestyle and diet are not only beneficial in the prevention and treatment of various diseases but also important in maintaining the overall health. Switching from unhealthy diet to health-friendly diet such as Mediterranean diet represents healthy lifestyle choice.

摘要

目的

总结地中海饮食在2型糖尿病预防和管理中的重要性。

数据来源

我们检索了截至2014年4月14日的PubMed电子数据库,使用以下关键词识别这些文章:“地中海饮食”和“糖尿病”。初步检索得到451条记录。检索策略没有语言和出版日期限制。仅根据标题和摘要评估研究的相关性。纳入我们综述的研究必须符合以下纳入标准:(1)随机临床试验、荟萃分析或系统评价,以及(2)提供有力证据证明该饮食是预防2型糖尿病、改善糖尿病患者血糖控制和心血管危险因素的一种方法。我们审查了49篇手稿,只有22篇符合我们的纳入标准。

研究选择

相关文献包括随机对照试验、荟萃分析或系统评价。

结果

基于多项研究,地中海饮食与2型糖尿病呈负相关,在2型糖尿病的管理中发挥重要作用。根据从各种研究中收集和评估的证据,我们得出结论,地中海饮食成分(如水果、蔬菜、坚果、豆类、全谷物、鱼类和适量饮用红酒)的组合和相互作用,这些成分含有必需营养素和促进健康的特性,包括高纤维、高镁、高抗氧化剂和高单不饱和脂肪酸(MUFA)。发现这些必需营养素和促进健康特性的相互作用和组合可降低体重、糖化血红蛋白(HbA1c)、低密度脂蛋白(LDL)、氧化应激,并提高高密度脂蛋白(HDL)水平;这有利于2型糖尿病的预防和预后改善。

结论

在现代社会,不良的饮食习惯加上缺乏体育活动与肥胖和2型糖尿病的风险相关。促进健康的生活方式和饮食不仅有利于各种疾病的预防和治疗,而且对维持整体健康也很重要。从不健康饮食转向健康友好型饮食,如地中海饮食,是一种健康的生活方式选择。

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