Capital Medical University School of Rehabilitation Medicine, China Rehabilitation Research Center, Beijing 100068, China.
Neural Regen Res. 2014 Aug 1;9(15):1474-84. doi: 10.4103/1673-5374.139465.
Mental practice is a new rehabilitation method that refers to the mental rehearsal of motor imagery content with the goal of improving motor performance. However, the relationship between activated regions and motor recovery after mental practice training is not well understood. In this study, 15 patients who suffered a first-ever subcortical stroke with neurological deficits affecting the right hand, but no significant cognitive impairment were recruited. 10 patients underwent mental practice combined with physical practice training, and 5 patients only underwent physical practice training. We observed brain activation regions after 4 weeks of training, and explored the correlation of activation changes with functional recovery of the affected hands. The results showed that, after 4 weeks of mental practice combined with physical training, the Fugl-Meyer assessment score for the affected right hand was significantly increased than that after 4 weeks of practice training alone. Functional MRI showed enhanced activation in the left primary somatosensory cortex, attenuated activation intensity in the right primary motor cortex, and enhanced right cerebellar activation observed during the motor imagery task using the affected right hand after mental practice training. The changes in brain cortical activity were related to functional recovery of the hand. Experimental findings indicate that cortical and cerebellar functional reorganization following mental practice contributed to the improvement of hand function.
心理练习是一种新的康复方法，它指的是对手动想象内容进行精神排练，以提高运动表现。然而，心理练习训练后激活区域与运动恢复之间的关系尚不清楚。在这项研究中，招募了 15 名首次患有皮质下卒中的患者，这些患者存在影响右手的神经功能缺损，但没有明显的认知障碍。其中 10 名患者接受了心理练习与身体练习相结合的训练，5 名患者仅接受了身体练习训练。我们观察了 4 周训练后的大脑激活区域，并探讨了激活变化与受影响手功能恢复之间的相关性。结果表明，经过 4 周的心理练习与身体训练相结合的训练后，受影响的右手 Fugl-Meyer 评估评分明显高于仅进行 4 周的身体训练后。功能磁共振成像显示，在使用受影响的右手进行运动想象任务时，左初级体感皮层的激活增强，右初级运动皮层的激活强度减弱，右小脑的激活增强。大脑皮质活动的变化与手部功能的恢复有关。实验结果表明，心理练习后皮质和小脑的功能重组有助于手部功能的改善。
