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神经退行性变与镜像失认症

Neurodegeneration and mirror image agnosia.

作者信息

Chandra Sadanandavalli Retnaswami, Issac Thomas Gregor

机构信息

Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

Department of Clinical Neurosciences, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

出版信息

N Am J Med Sci. 2014 Sep;6(9):472-7. doi: 10.4103/1947-2714.141647.

Abstract

BACKGROUND

Normal Percept with abnormal meaning (Agnosias) has been described from nineteenth century onwards. Later literature became abundant with information on the spectrum of Prosopagnosias. However, selective difficulty in identifying reflected self images with relatively better cognitive functions leads to problems in differentiating it from non-organic psychosis.

AIM

In the present study, we investigated patients with dementia who showed difficulty in identifying reflected self images while they were being tested for problems in gnosis with reference to identification of reflected objects, animals, relatives, and themselves and correlate with neuropsychological and radiological parameters.

PATIENTS AND METHODS

Five such patients were identified and tested with a 45 cm × 45 cm mirror kept at 30-cm distance straight ahead of them.

RESULTS

Mirror image agnosia is seen in patients with moderate stage posterior dementias who showed neuropsychological and radiological evidence of right parietal dysfunction.

CONCLUSION

Interpretation of reflected self images perception in real time probably involves distinct data-linking circuits in the right parietal lobe, which may get disrupted early in the course of the disease.

摘要

背景

从19世纪起就有关于正常感知却伴有异常意义(失认症)的描述。后来关于面孔失认症谱系的文献资料变得丰富起来。然而,在认知功能相对较好的情况下,识别镜中自我影像存在选择性困难,这导致难以将其与非器质性精神病区分开来。

目的

在本研究中,我们对患有痴呆症的患者进行了调查,这些患者在接受关于识别镜中物体、动物、亲属及自身的认知问题测试时,表现出识别镜中自我影像的困难,并将其与神经心理学和放射学参数相关联。

患者与方法

确定了5名此类患者,并让他们面对一面45厘米×45厘米的镜子进行测试,镜子放置在他们正前方30厘米处。

结果

镜像失认症见于中度晚期后部痴呆患者,这些患者显示出右侧顶叶功能障碍的神经心理学和放射学证据。

结论

实时解读镜中自我影像的感知可能涉及右侧顶叶中独特的数据连接回路,而这些回路可能在疾病早期就受到破坏。

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