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Early intermittent hypoxia induces proatherogenic changes in aortic wall macrophages in a murine model of obstructive sleep apnea.

作者信息

Gileles-Hillel Alex, Almendros Isaac, Khalyfa Abdelnaby, Zhang Shelley X, Wang Yang, Gozal David

机构信息

1 University of Chicago Chicago, Illinois.

出版信息

Am J Respir Crit Care Med. 2014 Oct 15;190(8):958-61. doi: 10.1164/rccm.201406-1149LE.

DOI:10.1164/rccm.201406-1149LE
PMID:25317468
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4299581/
Abstract
摘要

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本文引用的文献

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Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages.代谢功能障碍在脂肪组织巨噬细胞中驱动一种机制上独特的促炎表型。
Cell Metab. 2014 Oct 7;20(4):614-25. doi: 10.1016/j.cmet.2014.08.010. Epub 2014 Sep 18.
2
CD36, a scavenger receptor implicated in atherosclerosis.CD36，一种与动脉粥样硬化有关的清道夫受体。
Exp Mol Med. 2014 Jun 6;46(6):e99. doi: 10.1038/emm.2014.38.
3
Atherosclerosis--multiple pathways to lesional macrophages.动脉粥样硬化——病变巨噬细胞的多种途径。
Sci Transl Med. 2014 Jun 4;6(239):239ps2. doi: 10.1126/scitranslmed.3008922.
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Local proliferation dominates lesional macrophage accumulation in atherosclerosis.局部增殖主导动脉粥样硬化病灶中巨噬细胞的积累。
Nat Med. 2013 Sep;19(9):1166-72. doi: 10.1038/nm.3258. Epub 2013 Aug 11.
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Phenotypic polarization of macrophages in atherosclerosis.动脉粥样硬化中巨噬细胞的表型极化。
Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1120-6. doi: 10.1161/ATVBAHA.112.300173. Epub 2013 May 2.
6
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages.小鼠组织巨噬细胞的特征和多样性所依赖的基因表达谱和转录调控途径。
Nat Immunol. 2012 Nov;13(11):1118-28. doi: 10.1038/ni.2419. Epub 2012 Sep 30.
7
Association of obstructive sleep apnea with risk of serious cardiovascular events: a systematic review and meta-analysis.阻塞性睡眠呼吸暂停与严重心血管事件风险的关联：一项系统评价和荟萃分析。
Circ Cardiovasc Qual Outcomes. 2012 Sep 1;5(5):720-8. doi: 10.1161/CIRCOUTCOMES.111.964783. Epub 2012 Jul 24.
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Potential role of adult stem cells in obstructive sleep apnea.成体干细胞在阻塞性睡眠呼吸暂停中的潜在作用。
Front Neurol. 2012 Jul 11;3:112. doi: 10.3389/fneur.2012.00112. eCollection 2012.
9
Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions.髓外造血产生 Ly-6C(high)单核细胞，这些细胞浸润动脉粥样硬化病变。
Circulation. 2012 Jan 17;125(2):364-74. doi: 10.1161/CIRCULATIONAHA.111.061986. Epub 2011 Dec 5.
10
Obstructive sleep apnea and cardiovascular disease: a perspective and future directions.阻塞性睡眠呼吸暂停与心血管疾病：一种观点及未来方向
Prog Cardiovasc Dis. 2009 Mar-Apr;51(5):434-51. doi: 10.1016/j.pcad.2009.01.002.