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[实验性高血压动态变化中的微血管与肥大细胞]

[Microvessels and mast cells in the dynamics of experimental hypertension].

作者信息

Khugaeva V K

出版信息

Patol Fiziol Eksp Ter. 2014 Apr-Jun(2):3-7.

PMID:25318155
Abstract

In the dynamics of the experimental renal and hormonal hypertension in rats tracked change parameters such as blood pressure (BP), angiogenesis in microvessels of mesentery in small intestine, the number of mast cells (MC) surrounding microvessels. The same increase in BP there were qualitative and quantitative differences of angiogenesis in microvessels of mesentery in renal and hormonal hypertension. Overall it was the largest new form microvessels in branches with the smallest diameter (12-19 mkm) at hypertension compared with controls. MC response depended on the type of arterial hypertension. Structural changes of microcirculatory bed of mesentery in the small intestine of the rat depend not only on increased BP, but also reflect the characteristics of the pathogenesis of hypertension.

摘要

在大鼠实验性肾性和激素性高血压动态变化过程中,追踪了诸如血压(BP)、小肠系膜微血管中的血管生成、微血管周围肥大细胞(MC)数量等变化参数。在肾性和激素性高血压中,血压升高时系膜微血管生成存在质和量的差异。总体而言,与对照组相比,高血压时直径最小(12 - 19微米)的分支中新生微血管最多。MC反应取决于动脉高血压的类型。大鼠小肠系膜微循环床的结构变化不仅取决于血压升高,还反映了高血压发病机制的特点。

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Patol Fiziol Eksp Ter. 2014 Apr-Jun(2):3-7.
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