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晚期癌症患者呼吸困难的管理:一项叙述性综述。

Management of Breathlessness in Patients With Advanced Cancer: A Narrative Review.

作者信息

Lok Chan Wing

机构信息

Department of Clinical Oncology, Queen Mary Hospital, Hong Kong

出版信息

Am J Hosp Palliat Care. 2016 Apr;33(3):286-90. doi: 10.1177/1049909114554796. Epub 2014 Oct 15.

DOI:10.1177/1049909114554796
PMID:25318928
Abstract

Breathlessness is defined as "a subjective experience of breathing discomfort that consists of qualitatively distinct sensations that vary in intensity." It is a common and distressing symptom reported by patients with advanced malignancy. It occurs in up to 70% of patients with advanced cancer, and the symptom is aggravated with disease progression. This article reviews the etiology, assessment, and measurement of dyspnea in patients with advanced cancer. Because of its complex biopsychological etiology and manifestations, multidisciplinary approach with combination of both pharmacological and nonpharmacological interventions provides the best treatment plan for patients with dyspnea.

摘要

呼吸困难被定义为“一种呼吸不适的主观体验,由性质不同、强度各异的感觉组成”。它是晚期恶性肿瘤患者报告的常见且令人痛苦的症状。高达70%的晚期癌症患者会出现这种症状,且该症状会随着疾病进展而加重。本文综述了晚期癌症患者呼吸困难的病因、评估和测量方法。由于其复杂的生物心理病因和表现,采用药物和非药物干预相结合的多学科方法为呼吸困难患者提供了最佳治疗方案。

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1
Management of Breathlessness in Patients With Advanced Cancer: A Narrative Review.晚期癌症患者呼吸困难的管理:一项叙述性综述。
Am J Hosp Palliat Care. 2016 Apr;33(3):286-90. doi: 10.1177/1049909114554796. Epub 2014 Oct 15.
2
[Management of refractory breathlessness in patients with advanced disease].[晚期疾病患者难治性呼吸困难的管理]
Internist (Berl). 2016 Oct;57(10):978-982. doi: 10.1007/s00108-016-0122-y.
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[Dyspnea in lung cancer].[肺癌中的呼吸困难]
Rev Pneumol Clin. 2008 Apr;64(2):62-8. doi: 10.1016/j.pneumo.2008.03.003. Epub 2008 Jun 6.
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Symptom control and palliative care: management of breathlessness.症状控制与姑息治疗:呼吸困难的管理
Br J Hosp Med (Lond). 2009 Apr;70(4):212-6. doi: 10.12968/hmed.2009.70.4.41624.
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Breathlessness in cancer patients.癌症患者的呼吸急促
Eur J Cancer. 2008 May;44(8):1116-23. doi: 10.1016/j.ejca.2008.03.004.
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Managing dyspnea and cough.处理呼吸困难和咳嗽。
Hematol Oncol Clin North Am. 2002 Jun;16(3):557-77, viii. doi: 10.1016/s0889-8588(02)00019-9.
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[Dyspnea in cancer: causes and symptomatic treatment].[癌症中的呼吸困难:病因与对症治疗]
Ned Tijdschr Geneeskd. 1999 Nov 27;143(48):2421-4.
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Breathlessness in advanced disease. 2: Patient assessment and management.晚期疾病中的呼吸困难。2:患者评估与管理。
Nurs Times. 2010;106(44):12-4.
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The palliation of dyspnea in terminal disease.终末期疾病中呼吸困难的缓解
Am J Hosp Palliat Care. 1998 Nov-Dec;15(6):322-30. doi: 10.1177/104990919801500606.
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[Dyspnea in patients in palliative situations - the invisible symptom].[姑息治疗患者的呼吸困难——隐匿性症状]
Ther Umsch. 2024 Aug;81(4):145-150. doi: 10.23785/TU.2024.04.008.

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Exploring Psychotherapy Approaches for Dyspnea: A Systematic Review Protocol.探索治疗呼吸困难的心理治疗方法:一项系统评价方案
Palliat Med Rep. 2025 Feb 21;6(1):84-89. doi: 10.1089/pmr.2025.0002. eCollection 2025.
2
Nurses' perceptions to alleviate dyspnoea in inpatients with advanced cancer while receiving palliative care.护士对接受姑息治疗的晚期癌症住院患者缓解呼吸困难的认知。
Nurs Open. 2024 Jan;11(1):e2038. doi: 10.1002/nop2.2038.
3
Management of Refractory Breathlessness: a Review for General Internists.难治性呼吸困难的管理:普通内科医生的综述。
J Gen Intern Med. 2021 Apr;36(4):1035-1040. doi: 10.1007/s11606-020-06439-0. Epub 2021 Jan 19.
4
A Randomized Controlled Trial of a Non-pharmacological Intervention for Cancer-Related Dyspnea.一项针对癌症相关呼吸困难的非药物干预随机对照试验。
Front Oncol. 2020 Dec 1;10:591610. doi: 10.3389/fonc.2020.591610. eCollection 2020.
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Systemic corticosteroids for the management of cancer-related breathlessness (dyspnoea) in adults.全身用皮质类固醇治疗成人癌症相关性呼吸困难(气短)
Cochrane Database Syst Rev. 2019 Feb 20;2(2):CD012704. doi: 10.1002/14651858.CD012704.pub2.