Comparative analysis of Mg-dependent and Mg-independent HCO3(-) ATPases.

作者信息

Dzneladze S, Tsakadze L, Leladze M, Nozadze E, Arutinova N, Shioshvili L, Chkadua G

机构信息

Beritashvili Center of Experimental Biomedicine, 14 Gotua str, 0160, Tbilisi, Georgia,

出版信息

J Membr Biol. 2015 Feb;248(1):53-8. doi: 10.1007/s00232-014-9739-8. Epub 2014 Oct 16.

The comparative analysis between two enzymes, Mg-dependent and Mg-independent HCO3(-) ATPases, were studied in synaptosomal and microsomal membrane fractions of albino rat brain, using the method of kinetic analysis of the multi-sited enzyme systems. Therefore, it can be inferred that Mg-dependent HCO3(-) ATPase belongs to the group of "P-type" transporting ATPases. Mg-independent HCO3(-) ATPase with its kinetic properties may be attributed to the group of "Ecto" ATPases.