Løvlie Hanne, Immonen Elina, Gustavsson Emil, Kazancioğlu Erem, Arnqvist Göran
Animal Ecology, Department of Ecology and Genetics, Uppsala University, Norbyvägen 18D, 75236 Uppsala, Sweden
Animal Ecology, Department of Ecology and Genetics, Uppsala University, Norbyvägen 18D, 75236 Uppsala, Sweden.
Proc Biol Sci. 2014 Dec 7;281(1796):20141039. doi: 10.1098/rspb.2014.1039.
There is a growing awareness of the influence of mitochondrial genetic variation on life-history phenotypes, particularly via epistatic interactions with nuclear genes. Owing to their direct effect on traits such as metabolic and growth rates, mitonuclear interactions may also affect variation in behavioural types or personalities (i.e. behavioural variation that is consistent within individuals, but differs among individuals). However, this possibility is largely unexplored. We used mitonuclear introgression lines, where three mitochondrial genomes were introgressed into three nuclear genetic backgrounds, to disentangle genetic effects on behavioural variation in a seed beetle. We found within-individual consistency in a suite of activity-related behaviours, providing evidence for variation in personality. Composite measures of overall activity of individuals in behavioural assays were influenced by both nuclear genetic variation and by the interaction between nuclear and mitochondrial genomes. More importantly, the degree of expression of behavioural and life-history phenotypes was correlated and mitonuclear genetic variation affected expression of these concerted phenotypes. These results show that mitonuclear genetic variation affects both behavioural and life-history traits, and they provide novel insights into the maintenance of genetic variation in behaviour and personality.
人们越来越意识到线粒体遗传变异对生活史表型的影响，特别是通过与核基因的上位性相互作用。由于它们对代谢和生长速率等性状有直接影响，线粒体-核基因相互作用也可能影响行为类型或个性的变异（即个体内部一致但个体之间不同的行为变异）。然而，这种可能性在很大程度上尚未得到探索。我们使用线粒体-核基因渐渗系，将三个线粒体基因组渐渗到三个核遗传背景中，以厘清种子甲虫行为变异的遗传效应。我们在一系列与活动相关的行为中发现了个体内部的一致性，为个性变异提供了证据。行为测定中个体总体活动的综合测量受到核遗传变异以及核基因组与线粒体基因组之间相互作用的影响。更重要的是，行为和生活史表型的表达程度相关，线粒体-核基因变异影响这些协同表型的表达。这些结果表明，线粒体-核基因变异影响行为和生活史性状，并为行为和个性中遗传变异的维持提供了新的见解。
