Sevenster Dieuwke, Beckers Tom, Kindt Merel
Department of Clinical Psychology, University of Amsterdam, 1018 WB Amsterdam, The Netherlands Amsterdam Brain and Cognition Center, University of Amsterdam, 1018 WS Amsterdam, The Netherlands.
Department of Clinical Psychology, University of Amsterdam, 1018 WB Amsterdam, The Netherlands Amsterdam Brain and Cognition Center, University of Amsterdam, 1018 WS Amsterdam, The Netherlands Department of Psychology, University of Leuven, B-3000 Leuven, Belgium.
Learn Mem. 2014 Oct 15;21(11):580-4. doi: 10.1101/lm.035493.114. Print 2014 Nov.
Although disrupting reconsolidation is promising in targeting emotional memories, the conditions under which memory becomes labile are still unclear. The current study showed that post-retrieval changes in expectancy as an index for prediction error may serve as a read-out for the underlying processes engaged by memory reactivation. Minor environmental changes define whether retrieval induces memory reconsolidation or the initiation of a new memory trace even before fear extinction can be observed.
尽管破坏记忆再巩固在针对情感记忆方面很有前景，但记忆变得不稳定的条件仍不清楚。当前的研究表明，作为预测误差指标的检索后预期变化，可能是记忆重新激活所涉及的潜在过程的一种读出方式。微小的环境变化决定了检索是否会引发记忆再巩固，或者甚至在观察到恐惧消退之前就引发新记忆痕迹的形成。
