Korayem M, AlKofide E
Department of Pediatric Dentistry and Orthodontics, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
Orthod Craniofac Res. 2015 Feb;18(1):43-50. doi: 10.1111/ocr.12059. Epub 2014 Oct 17.
To study size and shape of the sella turcica in individuals with Down syndrome (DS) and compare them to matched controls without the syndrome.
The Department of Pediatric Dentistry and Orthodontics. Lateral cephalograms of sixty DS individuals and sixty controls were obtained with an age range of 12-22 years.
The length, depth, and diameter of the sella turcica were calculated. In addition, the shape of the sella turcica was described as either normal or with aberrations such as; oblique anterior wall, sella turcica bridging, extremely low sella turcica, irregularity in the posterior part of the dorsum sella, and pyramidal shape of the dorsum sella.
An increase in the diameter and depth of sella turcica was found more frequently in DS group as compared to controls (P < 0.05 and P < 0.0001, respectively). When the shape of the sella turcica was examined, a normal sella turcica shape was found less often in DS (P < 0.05). The most common abnormality detected was an oblique anterior wall (P < 0.05). A sella turcica bridge, irregularity in the posterior wall, and a pyramidal shape of sella turcica were present simultaneously in some individuals with DS (P < 0.01).
The sella turcica in DS differs in size and morphology when compared to individuals without the syndrome. The diameter and depth of the sella turcica in DS are larger than controls, with a tendency toward more abnormalities in the shape of sella turcica.
研究唐氏综合征（DS）患者蝶鞍的大小和形态，并与无该综合征的匹配对照组进行比较。
儿童牙科与正畸科。获取了60名DS患者和60名对照组的头颅侧位片，年龄范围为12至22岁。
计算蝶鞍的长度、深度和直径。此外，将蝶鞍的形态描述为正常或存在异常，如斜前壁、蝶鞍桥接、蝶鞍极低、鞍背后部不规则以及鞍背呈金字塔形。
与对照组相比，DS组蝶鞍直径和深度增加更为常见（分别为P < 0.05和P < 0.0001）。检查蝶鞍形态时，DS患者中正常蝶鞍形态较少见（P < 0.05）。检测到的最常见异常是斜前壁（P < 0.05）。一些DS患者同时存在蝶鞍桥接、后壁不规则和蝶鞍呈金字塔形（P < 0.01）。
与无该综合征的个体相比，DS患者的蝶鞍在大小和形态上有所不同。DS患者蝶鞍的直径和深度大于对照组，蝶鞍形态异常的倾向更大。
