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老年唐氏综合征患者伴颅底外侧骨折及骨化性蝶枕缝残留。

Vestiges of Ossified Spheno-occipital Suture in an Elderly Patient With Down Syndrome and Lateral Skull Base Fracture.

机构信息

Department of Oral and Craniomaxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany

Department of Oral and Craniomaxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.

出版信息

In Vivo. 2020 May-Jun;34(3):1427-1432. doi: 10.21873/invivo.11924.

DOI:10.21873/invivo.11924
PMID:32354941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7279811/
Abstract

BACKGROUND/AIM: Down syndrome (DS) patients often show characteristic changes in the skull, e.g. short cranial base. The synchondroses of the skull base have a significant influence on the shape of the skull. The sphenooccipital synchondrosis (SOS) is the last of the basal synchondroses to ossify. This report is about residual ossification of SOS in an elderly patient with DS.

CASE REPORT

The 65-year-old DS patient was polytraumatized by a fall. In the course of treatment, a purulent otitis externa on the right side was diagnosed, which had developed as a result of the fracture of the fossa glenoidalis. Computed tomograms of the skull base showed the fracture of the mandibular condyle, glenoid fossa and vestiges of SOS.

CONCLUSION

The coincidental finding of vestiges of SOS in an elderly patient with DS raises the question of whether cross-sectional skull base images can show differences in the ossification of SOS between DS patients and a normal population.

摘要

背景/目的:唐氏综合征(DS)患者的颅骨常表现出特征性改变,例如颅底短。颅骨基底的骺软骨结合对颅骨的形状有重要影响。蝶枕软骨结合(SOS)是最后一个发生骨化的基底骺软骨结合。本报告介绍了一例老年 DS 患者 SOS 残余骨化的病例。

病例报告

这位 65 岁的 DS 患者因跌倒而多处受伤。在治疗过程中,右侧诊断为化脓性外耳道炎,这是由于关节窝骨折引起的。颅骨底的计算机断层扫描显示下颌骨小头、关节窝和 SOS 的遗迹骨折。

结论

在老年 DS 患者中偶然发现 SOS 的遗迹,这引发了一个问题,即横断面颅骨底图像是否可以显示 DS 患者和正常人群中 SOS 骨化的差异。

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本文引用的文献

1
Neuroimaging assessment in Down syndrome: a pictorial review.唐氏综合征的神经影像学评估:图文综述
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Infection of the spheno-occipital synchondrosis: A morbid complication following adenoidectomy.蝶枕软骨结合感染:腺样体切除术后的一种严重并发症。
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Spheno-Occipital Synchondrosis Fusion Correlates with Cervical Vertebrae Maturation.蝶枕软骨结合融合与颈椎成熟相关。
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Human Foramen Magnum Area and Posterior Cranial Fossa Volume Growth in Relation to Cranial Base Synchondrosis Closure in the Course of Child Development.儿童发育过程中枕大孔区及后颅窝容积增长与颅底软骨结合闭合的关系
Neurosurgery. 2016 Nov;79(5):722-735. doi: 10.1227/NEU.0000000000001309.
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Size and shape of the sella turcica in subjects with Down syndrome.唐氏综合征患者蝶鞍的大小和形状。
Orthod Craniofac Res. 2015 Feb;18(1):43-50. doi: 10.1111/ocr.12059. Epub 2014 Oct 17.
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Earlier evidence of spheno-occipital synchondrosis fusion correlates with severity of midface hypoplasia in patients with syndromic craniosynostosis.蝶枕软骨结合融合的早期证据与综合征性颅缝早闭患者面中部发育不全的严重程度相关。
Plast Reconstr Surg. 2014 Sep;134(3):504-510. doi: 10.1097/PRS.0000000000000419.
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Premature closure of the spheno-occipital synchondrosis in Pfeiffer syndrome: a link to midface hypoplasia.普费弗综合征中蝶枕软骨结合过早闭合:与面中部发育不全的关联。
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