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Hartmann 手术与袢式结肠造口术治疗梗阻性直肠乙状结肠癌的比较。

Hartmann's procedure vs loop colostomy in the treatment of obstructive rectosigmoid cancer.

机构信息

University of Belgrade, Belgrade, Serbia ; Clinic for Emergency Surgery, Emergency center, Clinical centre of Serbia, Belgrade, Serbia.

Clinic for Emergency Surgery, Emergency center, Clinical centre of Serbia, Belgrade, Serbia.

出版信息

World J Emerg Surg. 2014 Oct 4;9(1):52. doi: 10.1186/1749-7922-9-52. eCollection 2014.

DOI:10.1186/1749-7922-9-52
PMID:25324896
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4198663/
Abstract

INTRODUCTION

Colorectal carcinoma is the most common malignant gastrointestinal tumour. There is still a considerable controversy when it comes to urgent surgical treatment of obstructive carcinoma of the left colon and rectum.

METHODS

Seventy-five patients from the randomized trial were followed up. This study was designed as a stratified randomized trial with four stratums according to age and ASA score (older/younger than 60 years and ASA score <>3). Each of the four groups is then divided into two sub-groups according to the operating technique: loop colostomy or Hartmann's procedure.

RESULTS

There were no difference found in hospitalization among the groups (loop colostomy vs. Hartmann's procedure) in the same stratus (P = 0.3192, P = 0.5760, P = 0.9023 respectively), except in the case of doing reconstructive procedure after loop colostomy (P = 0.0049) in the fourth stratum (patients younger than 60 years with ASA score lower than 3). Type of operation had no influence over the blood test values observed on admittance and during hospitalization (P = 0.319, P = 0.871, P = 0.7, P = 0.843, P = 0.52 respectively for the blood values). In terms of surgical and non-surgical complications it has been shown that there is no statistically significant difference between patients treated by two methods. Age, gender, ASA score, type of operation and surgical complications were not singled out as a risk factor for fatal outcome (P = 0.199, P = 0.155, P = 0.764, P = 0.452 and P = 0.724 respectively). The only factors that are singled out as a risk factor for death are the emergence of non-surgical complications and angina pectoris (P = 0.006, P = 0.001).

CONCLUSIONS

There is no difference in surgical treatment of large bowel obstruction caused by rectosigmoid carcinoma. Neither of those two methods showed significant advantage in treatment of large bowel obstruction caused by rectosigmoid cancer.

摘要

介绍

结直肠癌是最常见的胃肠道恶性肿瘤。对于左半结肠和直肠梗阻性癌的紧急手术治疗,仍存在相当大的争议。

方法

对随机试验中的 75 例患者进行随访。本研究设计为分层随机试验,根据年龄和 ASA 评分(大于/小于 60 岁和 ASA 评分<>3)分为 4 个分层。每个分层再根据手术方式分为两组:结肠造口术或 Hartmann 手术。

结果

在同一分层中,各组(结肠造口术与 Hartmann 手术)之间的住院时间无差异(P = 0.3192,P = 0.5760,P = 0.9023 分别),除了在第四分层(年龄小于 60 岁且 ASA 评分低于 3 的患者)中进行结肠造口术后重建手术时(P = 0.0049)。手术方式对入院时和住院期间的血液检查值无影响(P = 0.319,P = 0.871,P = 0.7,P = 0.843,P = 0.52 分别为血液值)。在手术和非手术并发症方面,两种方法治疗的患者之间无统计学差异。年龄、性别、ASA 评分、手术方式和手术并发症未被单独确定为死亡的危险因素(P = 0.199,P = 0.155,P = 0.764,P = 0.452 和 P = 0.724 分别)。唯一被确定为死亡危险因素的是非手术并发症和心绞痛(P = 0.006,P = 0.001)。

结论

在直肠乙状结肠癌引起的大肠梗阻的手术治疗中,两种方法没有差异。这两种方法在治疗直肠乙状结肠癌引起的大肠梗阻方面都没有明显优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/506a/4198663/35f7cc78686f/13017_2014_386_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/506a/4198663/35f7cc78686f/13017_2014_386_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/506a/4198663/35f7cc78686f/13017_2014_386_Fig1_HTML.jpg

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