社交焦虑中自我关注的神经关联
Neural correlates of self-focused attention in social anxiety.
作者信息
Boehme Stephanie, Miltner Wolfgang H R, Straube Thomas
机构信息
Laboratory of Psychophysiology and functional Imaging, Department of Psychiatry, Psychosomatics & Psychotherapy, University of Wüerzburg; Fuechsleinstr. 15, D-97080 Würzburg, Germany, Department of Biological and Clinical Psychology, Friedrich Schiller University Jena, Am Steiger 3//1, D-07743 Jena, Germany, and Institute of Medical Psychology and Systems Neuroscience, University of Muenster, Von-Esmarch-Str. 52, D-48149 Muenster, Germany Laboratory of Psychophysiology and functional Imaging, Department of Psychiatry, Psychosomatics & Psychotherapy, University of Wüerzburg; Fuechsleinstr. 15, D-97080 Würzburg, Germany, Department of Biological and Clinical Psychology, Friedrich Schiller University Jena, Am Steiger 3//1, D-07743 Jena, Germany, and Institute of Medical Psychology and Systems Neuroscience, University of Muenster, Von-Esmarch-Str. 52, D-48149 Muenster, Germany
Laboratory of Psychophysiology and functional Imaging, Department of Psychiatry, Psychosomatics & Psychotherapy, University of Wüerzburg; Fuechsleinstr. 15, D-97080 Würzburg, Germany, Department of Biological and Clinical Psychology, Friedrich Schiller University Jena, Am Steiger 3//1, D-07743 Jena, Germany, and Institute of Medical Psychology and Systems Neuroscience, University of Muenster, Von-Esmarch-Str. 52, D-48149 Muenster, Germany.
出版信息
Soc Cogn Affect Neurosci. 2015 Jun;10(6):856-62. doi: 10.1093/scan/nsu128. Epub 2014 Oct 17.
Socially anxious individuals tend to shift their attention away from external socially threatening cues and instead become highly self-focused. Such heightened self-focused attention has been suggested to be involved in the development and maintenance of social anxiety disorder. This study used functional magnetic resonance imaging to investigate the neural correlates of self-focused attention in 16 high socially anxious (HSA) and 16 low socially anxious (LSA) individuals. Participants were instructed to focus their attention either inwardly or outwardly during a simulated social situation. Results indicate hyperactivation of medial prefrontal cortex (mPFC), temporo-parietal junction (TPJ) and temporal pole during inward vs outward attention in HSA compared with LSA participants. Furthermore, activation of mPFC, right anterior insula, TPJ and posterior cingulate cortex was positively correlated with the trait of self-focused attention in HSA subjects. Results highlight the prominent role of the mPFC and other cortical structures in abnormal self-focused attention in social anxiety. Finally, findings for the insula suggest increased processing of bodily states that is related to the amount of habitual self-focused attention in social anxiety.
社交焦虑个体倾向于将注意力从外部具有社交威胁性的线索上转移开，转而高度关注自我。这种增强的自我关注被认为与社交焦虑障碍的发展和维持有关。本研究使用功能磁共振成像来调查16名高社交焦虑（HSA）个体和16名低社交焦虑（LSA）个体中自我关注的神经关联。参与者被指示在模拟社交情境中要么向内要么向外集中注意力。结果表明，与LSA参与者相比，HSA参与者在向内与向外注意力过程中，内侧前额叶皮质（mPFC）、颞顶联合区（TPJ）和颞极出现激活增强。此外，在HSA受试者中，mPFC、右侧前岛叶、TPJ和后扣带回皮质的激活与自我关注特质呈正相关。结果突出了mPFC和其他皮质结构在社交焦虑中异常自我关注方面的突出作用。最后，关于岛叶的研究结果表明，与社交焦虑中习惯性自我关注的程度相关的身体状态处理增加。
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