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[西班牙巴伦西亚儿科和住院医师中麻疹、风疹和腮腺炎免疫的血清学调查]

[Serological survey of measles, rubella and mumps immunity among pediatric and resident physicians, Valencia, Spain].

作者信息

Andani Cervera Joaquín, Castañeda Gordillo Patricia, Fuente Goig M Teresa, Giménez Martí M José, Alcaraz Soriano M Jesús, Gómez Pajares Fernando, Diez Domingo Javier, Boitos Cristina

出版信息

Rev Esp Salud Publica. 2014 Oct;88(5):653-9. doi: 10.4321/S1135-57272014000500009.

DOI:10.4321/S1135-57272014000500009
PMID:25327273
Abstract

BACKGROUND

Health workers are exposed to vaccine-preventable diseases. Therefore, vaccination programs are essential for preventing sanitary environment-acquired infections and avoiding additional damage to patients. The objectives were to estimate the prevalence of antibodies against measles, rubella and mumps among physicians of the Clinical Area of Children Diseases of the La Fe University Hospital (Valencia) and to study its relationship with history of disease, vaccination and professional status.

METHODS

Observational, cross-sectional and analytical study. All subjects underwent a serological test for detection of specific antibodies against measles, rubella and mumps. Some of them also completed a questionnaire about the history of disease and vaccination. A descriptive and relation analysis was performed to each disease.

RESULTS

97 physicians participated in the study. 75 participants (77,3%) had positive serology to measles, 85 (87,6%) to rubella and 68 (70,1%) to mumps. The logistic regression model showed a significant effect of age (OR 1,22) in the prevalence of antibodies against measles and a significant effect of sex (OR 5,16) in the prevalence of antibodies against rubella.

CONCLUSION

Given the high prevalence of seronegative young physicians and taking into account their professional activity, vaccination in this group would be recommended. Therefore it would be desirable to design strategies to achieve the accession of physicians to the vaccination program.

摘要

背景

卫生工作者会接触到可通过疫苗预防的疾病。因此,疫苗接种计划对于预防在卫生环境中获得的感染以及避免对患者造成额外损害至关重要。目的是评估拉费大学医院(巴伦西亚)儿童疾病临床区域的医生中麻疹、风疹和腮腺炎抗体的流行率,并研究其与疾病史、疫苗接种和职业状况的关系。

方法

观察性、横断面和分析性研究。所有受试者均接受了检测麻疹、风疹和腮腺炎特异性抗体的血清学检测。他们中的一些人还填写了一份关于疾病史和疫苗接种的问卷。对每种疾病进行了描述性和相关性分析。

结果

97名医生参与了该研究。75名参与者(77.3%)麻疹血清学呈阳性,85名(87.6%)风疹呈阳性,68名(70.1%)腮腺炎呈阳性。逻辑回归模型显示年龄(比值比1.22)对麻疹抗体流行率有显著影响,性别(比值比5.16)对风疹抗体流行率有显著影响。

结论

鉴于血清阴性年轻医生的高流行率,并考虑到他们的职业活动,建议对该群体进行疫苗接种。因此,设计策略以促使医生加入疫苗接种计划是可取的。

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