Snitsarenko O V
Vestn Dermatol Venerol. 1989(9):42-4.
Plasma kininogenesis components were studied in 110 patients with rosacea and in 3 groups of subjects at risk of developing this condition because of chronic gastrointestinal diseases, nervous system stress, or endocrine dysfunctions, conducive to rosacea. Changes in kininogenesis parameters similar to those detected in all rosacea patients were detected in all the 3 risk groups. Vasoactive polypeptide hyperproduction is a common component of rosacea pathogenesis. Vasoactive trend of the kinin action in kinin hyperproduction in rosacea induces vascular changes in the face and general vascular disorders, characteristic of this condition.
对110例酒渣鼻患者以及因慢性胃肠疾病、神经系统压力或内分泌功能障碍而有患酒渣鼻风险的3组受试者进行了血浆激肽生成成分的研究，这些因素易导致酒渣鼻。在所有3个风险组中均检测到与所有酒渣鼻患者中检测到的激肽生成参数变化相似的情况。血管活性多肽过度产生是酒渣鼻发病机制的一个共同组成部分。酒渣鼻激肽过度产生时激肽作用的血管活性趋势会导致面部血管变化和全身血管紊乱，这是该病的特征。
