Martinez Amy S, Eisenberg Laurie S, Boothroyd Arthur
Division of Clinical and Translational Research, House Research Institute, Los Angeles, California.
City University of New York, New York, New York.
Semin Hear. 2013;34(4):278-287. doi: 10.1055/s-0033-1356640.
The acoustic change complex (ACC) is a cortical auditory evoked potential elicited in response to a change in an ongoing sound. The ACC may have promise for assessing speech perception in infants and toddlers. In this preliminary study, the ACC was elicited in adults and young children in response to changes in speech stimuli representing vowel height /u/-/a/ and vowel place /u/-/i/ contrasts. The participants were adults with normal hearing ( = 3), children with normal hearing ( = 5), and children with mild to moderately severe bilateral sensorineural hearing loss ( = 5). The children with hearing loss were hearing aid users. The ages ranged from 2 years 3 months to 6 years 3months for the children and 44 to 55 years for the adults. Robust P1-N1-P2 responses were present for the adults and P1-N2 responses were present for all but the youngest child with hearing loss. The ACC response for the vowel place contrast was less robust than that for the vowel height contrast in one child with substantial hearing loss. The findings from this preliminary study support the conclusion that the ACC can be used successfully to assess auditory resolution in most young children.
听觉变化复合体（ACC）是一种皮质听觉诱发电位，由持续声音的变化引发。ACC可能有望用于评估婴幼儿的言语感知能力。在这项初步研究中，通过呈现代表元音高度/u/-/a/和元音位置/u/-/i/对比的言语刺激变化，在成人和幼儿中诱发ACC。参与者包括听力正常的成人（n = 3）、听力正常的儿童（n = 5）以及患有轻度至中度重度双侧感音神经性听力损失的儿童（n = 5）。听力损失儿童均使用助听器。儿童年龄范围为2岁3个月至6岁3个月，成人为44至55岁。成人呈现出明显的P1-N1-P2反应，除了听力损失最严重的幼儿外，所有儿童均呈现P1-N2反应。在一名听力损失严重的儿童中，元音位置对比的ACC反应不如元音高度对比的反应强烈。这项初步研究的结果支持以下结论：ACC能够成功用于评估大多数幼儿的听觉分辨能力。
