Cornelius Jack R, Kirisci Levent, Clark Duncan B
Center for Education and Drug Abuse Research (CEDAR), University of Pittsburgh, 3811 O'Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA.
Int J Med Biol Front. 2012;18(6):393-398.
Previous cross-sectional studies involving adults suggest that sexually transmitted diseases (STD) such as cocaine use disorders and opioid use disorders are associated with the development of sexually transmitted diseases (STD). However, it is less clear whether cannabis use disorders (CUD) are associated with the development of STDs, or whether those associations extend to adolescent populations. Longitudinal studies examining those associations are particularly scarce. The current report provides findings from a longitudinal study that examined the relationship between STD and CUD among youth transitioning to young adulthood.
The subjects in this longitudinal study were initially recruited when the index sons of these fathers were 10-12 years of age, and subsequent assessments were conducted at age 12-14, 16, 19, and 22. Multivariate logistic regression and path analyses were conducted.
At age 22, of the 345 subjects, 30 subjects were diagnosed with one or more STD, and 105 were diagnosed with a CUD. STDs were almost four times as common among those with a CUD as among those without a CUD, which was a significant difference. Path analyses demonstrated that peer deviance mediated the association between a measure of risk for SUD knows as the TLI and CUD, and that peer deviance mediated the association between TLI and STD. Risky sexual behaviors were common.
These finding suggest that cannabis use disorders (CUD) predispose to the development of sexually transmitted disorders (STD) among youth. These findings also suggest that peer deviance mediates the development of STD and of CUD among teenagers making the transition to young adulthood.
先前涉及成年人的横断面研究表明，诸如可卡因使用障碍和阿片类药物使用障碍等性传播疾病与性传播疾病（STD）的发生有关。然而，大麻使用障碍（CUD）是否与性传播疾病的发生有关，或者这些关联是否延伸至青少年人群，目前尚不清楚。检验这些关联的纵向研究尤为稀少。本报告提供了一项纵向研究的结果，该研究考察了向青年期过渡的青少年中性传播疾病与大麻使用障碍之间的关系。
这项纵向研究的受试者最初是在这些父亲的长子10 - 12岁时招募的，随后在12 - 14岁、16岁、19岁和22岁时进行评估。进行了多变量逻辑回归和路径分析。
在22岁时，345名受试者中，30人被诊断患有一种或多种性传播疾病，105人被诊断患有大麻使用障碍。患有大麻使用障碍的人中性传播疾病的发生率几乎是未患大麻使用障碍者的四倍，这是一个显著差异。路径分析表明，同伴偏差介导了作为SUD风险指标的TLI与大麻使用障碍之间的关联，并且同伴偏差介导了TLI与性传播疾病之间的关联。危险的性行为很常见。
这些发现表明，大麻使用障碍（CUD）使青少年易患性传播疾病（STD）。这些发现还表明，同伴偏差介导了向青年期过渡的青少年中性传播疾病和大麻使用障碍的发生。
