Department of Neurology, All India Institute of Medical Sciences, Delhi, India.
J Stroke. 2014 Sep;16(3):173-7. doi: 10.5853/jos.2014.16.3.173. Epub 2014 Sep 30.
Stroke in young adults has a special significance in developing countries, as it affects the most economically productive group of the society. We identified the risk factors and etiologies of young patients who suffered ischemic strokes and were admitted to a tertiary referral hospital in North India.
A retrospective review of case records from patients with ischemic stroke in the age range of 18-45 years was conducted from 2005 to 2010. Data regarding patients' clinical profiles, medical histories, diagnostic test results, and modified Rankin Scale scores at hospital discharge were examined. Stroke subtyping was conducted in accordance with the Trial of Org 10172 in Acute Stroke Treatment (TOAST) criteria.
Of the 2,634 patients admitted for ischemic stroke, 440 (16.7%) were in the 18-45 year age range and the majority (83.4%) were male. The most common risk factors were hypertension (34.4%) and dyslipidemia (26.5%). The most common subtype of stroke was undetermined (57%), followed by other determined causes (17.3%). Among the category of undetermined etiology, incomplete evaluation was the most common. Most of the patients demonstrated good functional outcomes.
Young adults account for 16.7% of all stroke patients in North India. Risk factors are relatively prevalent, and a high proportion of the patients are categorized under undetermined and other determined causes. The results highlight the needs for aggressive management of traditional risk factors and extensive patient work-ups to identify stroke etiology in India.
在发展中国家，年轻人发生卒中具有特殊意义，因为它影响到社会中最具生产力的群体。我们确定了在印度北部的一家三级转诊医院住院的年轻缺血性卒中患者的风险因素和病因。
对 2005 年至 2010 年期间年龄在 18-45 岁之间的缺血性卒中患者的病历进行回顾性分析。检查了患者的临床特征、病史、诊断性检查结果和出院时改良 Rankin 量表评分的数据。按照组织 10172 急性卒中治疗试验（TOAST）标准对卒中亚型进行分类。
在 2634 例缺血性卒中患者中，440 例（16.7%）年龄在 18-45 岁之间，大多数（83.4%）为男性。最常见的危险因素是高血压（34.4%）和血脂异常（26.5%）。最常见的卒中亚型为不明原因（57%），其次是其他明确病因（17.3%）。在不明原因病因分类中，评估不完整是最常见的原因。大多数患者的功能结局良好。
在印度北部，年轻人占所有卒中患者的 16.7%。危险因素较为常见，很大一部分患者被归类为不明原因和其他明确病因。研究结果突出表明，需要积极管理传统危险因素，并对患者进行广泛检查以确定印度的卒中病因。
