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意大利费拉拉市青年人脑卒中的发病与预后:一项基于人群的研究。

Incidence and prognosis of stroke in young adults: a population-based study in Ferrara, Italy.

机构信息

Section of Clinical Neurology, Department of Medical and Surgical Sciences of Communication and Behaviour, University of Ferrara, Corso della Giovecca 203, 44121 Ferrara, Italy.

出版信息

Neurol Sci. 2012 Feb;33(1):53-8. doi: 10.1007/s10072-011-0654-9. Epub 2011 Jun 22.

DOI:10.1007/s10072-011-0654-9
PMID:21695657
Abstract

The reported annual incidence of juvenile stroke ranges from 9 to 47 cases per 100,000 inhabitants. We sought to estimate the incidence of first-ever stroke in young adults through a population-based stroke registry in a well-defined and stable population. We planned to collect all cases of new stroke in people aged 15-44 years in Ferrara, Italy, over the period 2002-2007. During the surveillance period, a first-ever stroke was diagnosed in 39 patients, giving a mean annual crude incidence rate of 12.1 cases per 100,000 person-years (95% CI 8.6-16.5), 9.1 when adjusted to the European population. The overall 30-day case fatality rate was 7.7, 21.4% for hemorrhagic stroke. The incidence rate was in the range of estimates detected in western countries. The case-fatality rate was lower than that reported in less recent studies. The stroke subtype predicted the probability of death and the outcome.

摘要

据报道,青少年脑卒中的年发病率为每 10 万人中有 9 至 47 例。我们试图通过在一个明确且稳定的人群中进行基于人群的脑卒中登记来估计年轻人首次脑卒中的发病率。我们计划在意大利费拉拉市收集 2002 年至 2007 年期间年龄在 15-44 岁的所有新发脑卒中患者。在监测期间,共诊断出 39 例首次脑卒中,粗年发病率为 12.1/10 万人年(95%CI8.6-16.5),调整至欧洲人口后为 9.1/10 万人年。总的 30 天病死率为 7.7%,出血性脑卒中为 21.4%。发病率在西方国家的估计范围内。病死率低于近期报道的研究结果。脑卒中亚型预测了死亡概率和结局。

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