Apice G, Beneduce G, Bruni G S, D'Aprile M, Perna M, Silvestro P, Villari P, Pergola M
Clin Ter. 1989 Nov 15;131(3):177-82.
In the treatment of infections arisen in neoplastic patients without neutropenia, 2 antibiotic combinations (aztreonam + oxacillin vs tobramycin + cefoxitin), have been compared with regard to therapeutic effectiveness and tolerability. Twenty patients (age: 30-75) have been studied. Tolerability of both combinations was excellent. Results of this study showed a lower percentage of superinfections and a higher percentage of cure in patients treated with the combination aztreonam + oxacillin, even if the data were not statistically significant.
在治疗无中性粒细胞减少的肿瘤患者发生的感染时，比较了两种抗生素联合用药方案（氨曲南+苯唑西林与妥布霉素+头孢西丁）的治疗效果和耐受性。研究了20例患者（年龄：30 - 75岁）。两种联合用药方案的耐受性都很好。本研究结果显示，使用氨曲南+苯唑西林联合用药方案治疗的患者，其二重感染发生率较低，治愈率较高，尽管数据无统计学意义。
