Davenport Andrew
UCL Centre for Nephrology, Royal Free Hospital, University College London Medical School, Rowland Hill Street, London, NW3 2PF, UK.
Pediatr Nephrol. 2015 Dec;30(12):2053-60. doi: 10.1007/s00467-014-2968-3. Epub 2014 Oct 21.
Dialysis is a life-sustaining treatment for patients with end-stage kidney disease. In a different context, for many patients this treatment is the focal point around which their life revolves, not only due to the time spent travelling to and from treatment sessions and the time dedicated to the dialysis treatment itself, but also due to the accompanying dietary and fluid restrictions and medication burden. Wearable and portable dialysis devices could potentially improve patient quality of life by allowing patients to continue with their daily activities of life while undergoing dialysis, as well as by loosening-or removing entirely-dietary and fluid restrictions and reducing pill burden. Advances in nanotechnology manufacturing coupled with advances in electronics and miniaturisation have allowed a new generation of wearable and portable dialysis devices to be developed which are now undergoing large animal and patient clinical trials. We are therefore potentially at a new dawn in the treatment of dialysis patients with the first generation of wearable and portable dialysis devices, which may well revolutionise the treatment and quality of life for patients with end-stage kidney disease.
透析是终末期肾病患者维持生命的治疗方法。在不同的背景下，对许多患者来说，这种治疗是他们生活围绕的焦点，这不仅是因为往返治疗过程所花费的时间以及用于透析治疗本身的时间，还因为随之而来的饮食和液体限制以及药物负担。可穿戴和便携式透析设备有可能改善患者的生活质量，因为它能让患者在接受透析时继续日常活动，还能放宽或完全解除饮食和液体限制，并减轻服药负担。纳米技术制造的进步，再加上电子学和小型化的进步，使得新一代可穿戴和便携式透析设备得以开发，目前这些设备正在进行大型动物和患者临床试验。因此，随着第一代可穿戴和便携式透析设备的出现，我们可能正处于透析患者治疗的新起点，这很可能会彻底改变终末期肾病患者的治疗方式和生活质量。
