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如何让更多已发表的研究成果真实可靠。

How to make more published research true.

作者信息

Ioannidis John P A

机构信息

Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford, California, United States of America; Department of Medicine, Stanford Prevention Research Center, Stanford, California, United States of America; Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, United States of America; Department of Statistics, Stanford University School of Humanities and Sciences, Stanford, California, United States of America.

出版信息

PLoS Med. 2014 Oct 21;11(10):e1001747. doi: 10.1371/journal.pmed.1001747. eCollection 2014 Oct.

DOI:10.1371/journal.pmed.1001747
PMID:25334033
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4204808/
Abstract

In a 2005 paper that has been accessed more than a million times, John Ioannidis explained why most published research findings were false. Here he revisits the topic, this time to address how to improve matters. Please see later in the article for the Editors' Summary.

摘要

在一篇访问量超过百万次的2005年论文中，约翰·约阿尼季斯解释了为何大多数已发表的研究结果是错误的。在此他再次探讨这一话题，此次是为了解决如何改善这种情况。编辑总结请见本文后文。

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本文引用的文献

[1]
Scientific Utopia: II. Restructuring Incentives and Practices to Promote Truth Over Publishability.

Perspect Psychol Sci. 2012-11

[2]
Is the Replicability Crisis Overblown? Three Arguments Examined.

Perspect Psychol Sci. 2012-11

[3]
Impact of peer review on reports of randomised trials published in open peer review journals: retrospective before and after study.

BMJ. 2014-7-1

[4]
Evidence based medicine: a movement in crisis?

BMJ. 2014-6-13

[5]
Cancer-gene data sharing boosted.

Nature. 2014-6-12

[6]
Assessing value in biomedical research: the PQRST of appraisal and reward.

JAMA. 2014-8-6

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Sea change in open science and data sharing: leadership by industry.

Circ Cardiovasc Qual Outcomes. 2014-7

[8]
Research on peer review and biomedical publication: furthering the quest to improve the quality of reporting.

JAMA. 2014-3-12

[9]
Making prospective registration of observational research a reality.

Sci Transl Med. 2014-2-19

[10]
Scientific method: statistical errors.

Nature. 2014-2-13

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