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[妊娠高血压综合征患者红细胞免疫功能的初步研究]

[Preliminary study on the immune function of red cells in patients with pregnancy-induced hypertension].

作者信息

Guo F, Qian S Z

出版信息

Zhonghua Fu Chan Ke Za Zhi. 1989 Jul;24(4):215-6, 252.

PMID:2533548
Abstract

This study compared the immune adherent function of red cells, circulating immune complex (CIC) and T lymphocyte immune function in cases of pregnancy induced hypertension (30 cases) and normal pregnancy (30 cases). In the former group the rosette rate of red cells C3b receptor was 8.8 +/- 3.2% (normal rate: 19.4 +/- 6.0%), and rosette rate of E-RFC was 46 +/- 2 +/- 7.3% (normal rate: 62.3 +/- 6.4%). In women with normal pregnancy, the former was 16.9 +/- 4.8%, and the latter was 58.0 +/- 8.3%. In women with pregnancy induced hypertension, the immune adherent function of red cells and T lymphocyte immune function were both lower than those in normal pregnant women, while CIC was higher. In normal pregnant women, the immune adherent function of red cells and T lymphocyte immune function were lower than those in the non-pregnant, while CIC was higher. The mechanism and significance of the red cells immunological adherent function in pregnancy induced hypertension were discussed.

摘要

本研究比较了30例妊娠高血压综合征患者和30例正常孕妇的红细胞免疫黏附功能、循环免疫复合物(CIC)及T淋巴细胞免疫功能。妊娠高血压综合征组红细胞C3b受体花环率为8.8±3.2%(正常率:19.4±6.0%),E玫瑰花结形成细胞(E-RFC)花环率为46±2±7.3%(正常率:62.3±6.4%)。正常孕妇组红细胞C3b受体花环率为16.9±4.8%,E-RFC花环率为58.0±8.3%。妊娠高血压综合征患者红细胞免疫黏附功能和T淋巴细胞免疫功能均低于正常孕妇,而CIC则高于正常孕妇。正常孕妇红细胞免疫黏附功能和T淋巴细胞免疫功能低于非孕妇女,而CIC高于非孕妇女。文中讨论了妊娠高血压综合征时红细胞免疫黏附功能变化的机制及意义。

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