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评估多次CT扫描相关的癌症终生风险。

Estimating the lifetime risk of cancer associated with multiple CT scans.

作者信息

Ivanov V K, Kashcheev V V, Chekin S Yu, Menyaylo A N, Pryakhin E A, Tsyb A F, Mettler F A

机构信息

Federal State Institution Medical Radiological Research Centre of the Russian Ministry of Health, 4 Korolyov Street, Obninsk, Kaluga region, 249036, Russia.

出版信息

J Radiol Prot. 2014 Dec;34(4):825-41. doi: 10.1088/0952-4746/34/4/825. Epub 2014 Oct 23.

DOI:10.1088/0952-4746/34/4/825
PMID:25340355
Abstract

Multiple CT scans are often done on the same patient resulting in an increased risk of cancer. Prior publications have estimated risks on a population basis and often using an effective dose. Simply adding up the risks from single scans does not correctly account for the survival function. A methodology for estimating personal radiation risks attributed to multiple CT imaging using organ doses is presented in this article. The estimated magnitude of the attributable risk fraction for the possible development of radiation-induced cancer indicates the necessity for strong clinical justification when ordering multiple CT scans.

摘要

同一患者常进行多次CT扫描,这会增加患癌风险。先前的出版物已在人群基础上估算风险,且通常使用有效剂量。简单累加单次扫描的风险并不能正确考虑生存函数。本文提出了一种使用器官剂量估算多次CT成像所致个人辐射风险的方法。辐射诱发癌症可能发生的归因风险分数的估计值表明,在开具多次CT扫描医嘱时,需要有充分的临床理由。

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