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尼泊尔上木斯塘高海拔社区翼状胬肉的患病率及相关危险因素

Prevalence of and associated risk factors for pterygium in the high altitude communities of Upper Mustang, Nepal.

作者信息

Maharjan I M, Shreshth E, Gurung B, Karmacharya S

机构信息

Himalaya Eye Hospital, Pokhara, Nepal.

出版信息

Nepal J Ophthalmol. 2014 Jan;6(11):65-70. doi: 10.3126/nepjoph.v6i1.10774.

Abstract

OBJECTIVE

To determine the prevalenceof and associated risk factors for pterygiumin the high altitude communities of the Upper Mustang region of Nepal, near the Tibet border.

MATERIALS AND METHODS

Six villages of the Upper Mustang were selected based on the concentration of population. All subjects were permanent residents aged 16 years and older, and recruited through a household census with mobilization of local monks who had been trained as interviewers, and people were invited to attend the eye clinic for a complete examination. A cross-sectional studywas conducted which included the parameters oflaterality, severity, occupation, age, sex and altitude of residence.

RESULTS

The study population comprised 1,319 individuals of which 637 (48.29%) weremale and682 (51.71%) were female.The overall prevalence of pterygium, was 10.08% (133 of 1,319), with 42.86% for males and 57.14% for females. The mean age of the subjects was45.83 years and the mean SD 17.94. The majority of the subjects had a unilateral pterygium. The right eye(n=63) was predominately affected, in 57.80% of the total subjects. Farmers and construction workers, which comprised of 36.09% and 28.57% respectively, had a higher prevalence of pterygium. The most affected age group was the 66 to 75 years group (n=31: 23.31%). The prevalence increased linearly with age. The severe Grade III and Grade IV pterygium were predominant in the age group of 56-65 years, comprising 28.58% of all the cases;the less severe Grade I was also predominant in the same age group,with 23.56%, and Grade II (0-2 mm) was predominant in the age group of 46-55, with 31.03%.

CONCLUSION

Pterygiumisa significant public health problem in the high altitude communities of Nepal. It is more prevalent amongst the farmers than in the other professionals.

摘要

目的

确定尼泊尔上木斯塘地区靠近西藏边境的高海拔社区翼状胬肉的患病率及相关危险因素。

材料与方法

根据人口密度选择上木斯塘的6个村庄。所有受试者均为16岁及以上的常住居民,通过家庭普查招募,动员经过培训作为访谈员的当地僧侣,并邀请人们前往眼科诊所进行全面检查。进行了一项横断面研究,包括患侧、严重程度、职业、年龄、性别和居住海拔等参数。

结果

研究人群包括1319人,其中男性637人(48.29%),女性682人(51.71%)。翼状胬肉的总体患病率为10.08%(1319人中的133人),男性为42.86%,女性为57.14%。受试者的平均年龄为45.83岁,平均标准差为17.94。大多数受试者患有单侧翼状胬肉。右眼(n = 63)受影响为主,占总受试者的57.80%。农民和建筑工人的翼状胬肉患病率较高,分别占36.09%和28.57%。受影响最严重的年龄组是66至75岁组(n = 31:23.31%)。患病率随年龄呈线性增加。严重的III级和IV级翼状胬肉在56 - 65岁年龄组中占主导地位,占所有病例的28.58%;较轻的I级在同一年龄组中也占主导地位,为23.56%,II级(0 - 2mm)在46 - 55岁年龄组中占主导地位,为31.03%。

结论

翼状胬肉是尼泊尔高海拔社区的一个重要公共卫生问题。在农民中比在其他职业人群中更普遍。

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