Li Jiang-yan, Li Qian, Fang Qiang
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2014 Jun;26(3):326-31.
Malaria remains a serious public health problem, especially in developing countries. With the deepening of the understanding of vivax malaria, Plasmodium vivax is also attracting more and more attention. An effective drug treatment is the foundation of controlling or even eliminating malaria. In recent years, more and more reports of chloroquine-resistance Plasmodium vivax have been reported. Plasmodium vivax chloroquine resistance has been a focus problem in vivax malaria prevention and treatment. In this paper, the research progress on distribution situation, detection methods and molecular markers of Plasmodium vivax chloroquine resistance is summarized.
疟疾仍然是一个严重的公共卫生问题，尤其是在发展中国家。随着对间日疟原虫认识的不断深入，间日疟原虫也越来越受到关注。有效的药物治疗是控制甚至消除疟疾的基础。近年来，越来越多关于氯喹抗性间日疟原虫的报道出现。间日疟原虫对氯喹的抗性一直是间日疟防治中的一个焦点问题。本文就间日疟原虫氯喹抗性的分布情况、检测方法及分子标记等方面的研究进展进行综述。
