Pinheiro C E, Poletto M I, Pinheiro C R, Negrato M L
Rev Odontol Univ Sao Paulo. 1989 Apr-Jun;3(2):334-7.
The enzyme glucosyltransferase plays an important role in plaque formation and growth. Therefore, chemical inhibition of glucosyltransferase may become an effective method for plaque control. In this investigation we have evaluated the effects of some antiplaque substances (chlorhexidine, cetylpiridinium chloride, iodine, sodium fluoride and sodium dodecyl sulfate) on glucosyltransferase activity. Our results revealed that iodine was the most effective inhibitor. Based on in vitro glucosyltransferase inhibition we may suggest that topical iodine could be an auxiliary method for plaque control.
葡糖基转移酶在菌斑形成和生长过程中起着重要作用。因此，化学抑制葡糖基转移酶可能成为控制菌斑的一种有效方法。在本研究中，我们评估了一些抗菌斑物质（洗必泰、西吡氯铵、碘、氟化钠和十二烷基硫酸钠）对葡糖基转移酶活性的影响。我们的结果显示，碘是最有效的抑制剂。基于体外葡糖基转移酶抑制作用，我们认为局部应用碘可能是一种辅助控制菌斑的方法。
