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基因组在线数据库（GOLD）v.5：一个基于四级（元）基因组计划分类的元数据管理系统。

The Genomes OnLine Database (GOLD) v.5: a metadata management system based on a four level (meta)genome project classification.

作者信息

Reddy T B K, Thomas Alex D, Stamatis Dimitri, Bertsch Jon, Isbandi Michelle, Jansson Jakob, Mallajosyula Jyothi, Pagani Ioanna, Lobos Elizabeth A, Kyrpides Nikos C

机构信息

Prokaryotic Super Program, DOE Joint Genome Institute, Walnut Creek, CA 94598, USA

Prokaryotic Super Program, DOE Joint Genome Institute, Walnut Creek, CA 94598, USA.

出版信息

Nucleic Acids Res. 2015 Jan;43(Database issue):D1099-106. doi: 10.1093/nar/gku950. Epub 2014 Oct 27.

DOI:10.1093/nar/gku950
PMID:25348402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4384021/
Abstract

The Genomes OnLine Database (GOLD; http://www.genomesonline.org) is a comprehensive online resource to catalog and monitor genetic studies worldwide. GOLD provides up-to-date status on complete and ongoing sequencing projects along with a broad array of curated metadata. Here we report version 5 (v.5) of the database. The newly designed database schema and web user interface supports several new features including the implementation of a four level (meta)genome project classification system and a simplified intuitive web interface to access reports and launch search tools. The database currently hosts information for about 19,200 studies, 56,000 Biosamples, 56,000 sequencing projects and 39,400 analysis projects. More than just a catalog of worldwide genome projects, GOLD is a manually curated, quality-controlled metadata warehouse. The problems encountered in integrating disparate and varying quality data into GOLD are briefly highlighted. GOLD fully supports and follows the Genomic Standards Consortium (GSC) Minimum Information standards.

摘要

基因组在线数据库（GOLD；http://www.genomesonline.org）是一个全面的在线资源，用于编目和监测全球范围内的基因研究。GOLD提供了完整和正在进行的测序项目的最新状态以及一系列经过精心策划的元数据。在此，我们报告该数据库的第5版（v.5）。新设计的数据库架构和网络用户界面支持多个新功能，包括实施四级（元）基因组项目分类系统以及一个简化直观的网络界面，用于访问报告和启动搜索工具。该数据库目前存储了约19200项研究、56000个生物样本、56000个测序项目和39400个分析项目的信息。GOLD不仅仅是全球基因组项目的编目，还是一个经过人工策划、质量控制的元数据仓库。文中简要强调了将不同质量的数据整合到GOLD中所遇到的问题。GOLD完全支持并遵循基因组标准联盟（GSC）的最低信息标准。

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