Biological Data Management and Technology Center, Computational Research Division Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, 94720 USA and Microbial Genome and Metagenome Program, Department of Energy Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA, 94598 USA.
Nucleic Acids Res. 2014 Jan;42(Database issue):D568-73. doi: 10.1093/nar/gkt919. Epub 2013 Oct 16.
IMG/M (http://img.jgi.doe.gov/m) provides support for comparative analysis of microbial community aggregate genomes (metagenomes) in the context of a comprehensive set of reference genomes from all three domains of life, as well as plasmids, viruses and genome fragments. IMG/M's data content and analytical tools have expanded continuously since its first version was released in 2007. Since the last report published in the 2012 NAR Database Issue, IMG/M's database architecture, annotation and data integration pipelines and analysis tools have been extended to copewith the rapid growth in the number and size of metagenome data sets handled by the system. IMG/M data marts provide support for the analysis of publicly available genomes, expert review of metagenome annotations (IMG/M ER: http://img.jgi.doe.gov/mer) and Human Microbiome Project (HMP)-specific metagenome samples (IMG/M HMP: http://img.jgi.doe.gov/imgm_hmp).
IMG/M（http://img.jgi.doe.gov/m）支持在一套全面的参考基因组的背景下，对微生物群落总基因组（宏基因组）进行比较分析，这些参考基因组涵盖了生命的所有三个领域，以及质粒、病毒和基因组片段。自 2007 年首次发布以来，IMG/M 的数据内容和分析工具不断扩展。自 2012 年 NAR 数据库专刊上发表的上一份报告以来，IMG/M 的数据库架构、注释和数据集成管道以及分析工具已经扩展，以应对系统处理的宏基因组数据集数量和大小的快速增长。IMG/M 数据集市为分析公共可用基因组、宏基因组注释的专家审查（IMG/M ER：http://img.jgi.doe.gov/mer）以及人类微生物组计划（HMP）特定的宏基因组样本（IMG/M HMP：http://img.jgi.doe.gov/imgm_hmp）提供支持。
