Gagnaire Béatrice, Bado-Nilles Anne, Betoulle Stéphane, Amara Rachid, Camilleri Virginie, Cavalié Isabelle, Chadili Edith, Delahaut Laurence, Kerambrun Elodie, Orjollet Daniel, Palluel Olivier, Sanchez Wilfried
Institut de Radioprotection et de Sureté Nucléaire (IRSN), PRP-ENV, SERIS, LECO, Centre de Cadarache, Bât 186, B.P. 3, 13115, Saint-Paul-Lez-Durance, France,
Ecotoxicology. 2015 Jan;24(1):215-31. doi: 10.1007/s10646-014-1374-8. Epub 2014 Oct 28.
To characterize environmental risks linked to former uranium mines in the Limousin region of France, a study was conducted on fish health effects from uranium releases. Two private ponds were compared in this study, one with uranium contamination and one background site, upstream of the mining zone. Roach, Rutilus rutilus, were caged for 28 days in both ponds. Physico-chemical parameters of water and sediments and bioaccumulation of metals in several organs were determined. After 14 and 28 days of caging, immune, oxidative stress, biotransformation, neurotoxicity and physiological parameters were measured. Iron and aluminium were quantified in the water of both sites; however, barium and manganese were only present in the water of the uranium contaminated site. Uranium was present in both sites but at very different concentrations. The sediments from the uranium contaminated site contained high levels of radioactive elements coming from the disintegration chain of uranium. Results of biological parameters indicated stimulation of immune parameters and of oxidative stress and a decrease of AChE in fish caged in the uranium contaminated pond compared to the uranium-free pond. Overall, the results determined roach health status in the context of pollution from poly-metallic mining. The data strengthen our knowledge of the environmental risk assessment associated with radioactive substances in the environment.
为了描述与法国利穆赞地区以前的铀矿相关的环境风险，开展了一项关于铀释放对鱼类健康影响的研究。本研究比较了两个私人池塘，一个受到铀污染，另一个作为背景点，位于矿区上游。将拟鲤（Rutilus rutilus）置于两个池塘中笼养28天。测定了水和沉积物的理化参数以及几种器官中金属的生物累积情况。在笼养14天和28天后，测量了免疫、氧化应激、生物转化、神经毒性和生理参数。对两个地点的水中铁和铝进行了定量；然而，钡和锰仅存在于受铀污染地点的水中。两个地点都存在铀，但浓度差异很大。受铀污染地点的沉积物含有来自铀衰变链的高水平放射性元素。生物学参数结果表明，与无铀池塘相比，置于受铀污染池塘中的鱼类免疫参数、氧化应激受到刺激，乙酰胆碱酯酶降低。总体而言，研究结果确定了多金属采矿污染背景下拟鲤的健康状况。这些数据增强了我们对与环境中放射性物质相关的环境风险评估的认识。
