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复发性多软骨炎

Relapsing polychondritis.

作者信息

Sosada Beata, Loza Katarzyna, Bialo-Wojcicka Ewelina

机构信息

Department of Dermatology, Miedzyleski Specialist Hospital in Warsaw, ul. Bursztynowa 2, 04-479 Warsaw, Poland.

出版信息

Case Rep Dermatol Med. 2014;2014:791951. doi: 10.1155/2014/791951. Epub 2014 Sep 30.

DOI:10.1155/2014/791951
PMID:25349745
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4198788/
Abstract

Relapsing polychondritis (RP) is a rare systemic disease characterized by recurrent, widespread chondritis of the auricular, nasal, and tracheal cartilages. Additional clinical features include audiovestibular dysfunction, ocular inflammation, vasculitis, myocarditis, and nonerosive arthritis. Although the cause remains unknown, the etiology is suspected to be autoimmune. We describe a case of a 31-year-old woman with a four-month history of bilateral auricular and nasal chondritis. Infectious and neoplastic diseases were excluded by imaging and laboratory examinations. RP was diagnosed based on three McAdam's criteria. The patient was medicated with oral prednisolone and methotrexate with positive clinical response. In this case clinical history and detailed physical examination were fundamental in concluding the correct diagnosis and administrating the appropriate medication.

摘要

复发性多软骨炎(RP)是一种罕见的全身性疾病,其特征为耳廓、鼻和气管软骨反复发生广泛性软骨炎。其他临床特征包括听前庭功能障碍、眼部炎症、血管炎、心肌炎和非侵蚀性关节炎。尽管病因尚不清楚,但怀疑其病因是自身免疫性的。我们描述了一名31岁女性病例,她有四个月的双侧耳廓和鼻软骨炎病史。通过影像学和实验室检查排除了感染性和肿瘤性疾病。根据三条麦卡姆标准诊断为RP。患者接受口服泼尼松龙和甲氨蝶呤治疗,临床反应良好。在该病例中,临床病史和详细的体格检查对于做出正确诊断和给予适当治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/604d/4198788/f3c4aab239ef/CRIDM2014-791951.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/604d/4198788/434e333b0a64/CRIDM2014-791951.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/604d/4198788/f3c4aab239ef/CRIDM2014-791951.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/604d/4198788/434e333b0a64/CRIDM2014-791951.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/604d/4198788/f3c4aab239ef/CRIDM2014-791951.002.jpg

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