Center of Micro and Nanochemistry and Engineering, Organische Chemie I, Universität Siegen, Adolf-Reichwein-Str. 2, D-57068 Siegen, Germany.
Chem Soc Rev. 2015 Jan 7;44(1):136-60. doi: 10.1039/c4cs00263f. Epub 2014 Oct 30.
This review highlights the currently exploited working concepts of lab-on-a-molecule probes, with a particular focus on what is required for multianalyte detection and quantification in competitive assays. Both, chemosensor and chemodosimeter approaches are considered. The multifaceted design strategies and the orthogonal protocols are evaluated in order to identify and categorise the successful conceptions and to single out unknown territory and challenges for future work.
本文重点介绍了当前在分子级实验室探针中所应用的工作原理，特别关注在竞争分析中用于多分析物检测和定量所需的内容。同时考虑了化学传感器和化学计量计方法。评估了多方面的设计策略和正交方案，以识别和分类成功的构想，并找出未来工作中的未知领域和挑战。
