外阴痛采用局部雌二醇和睾酮治疗。
The treatment of vestibulodynia with topical estradiol and testosterone.
机构信息
Obstetrics and Gynecology, The Center for Vulvovaginal Disorders Washington, DC, USA.
出版信息
Sex Med. 2013 Aug;1(1):30-3. doi: 10.1002/sm2.4.
INTRODUCTION
Combined hormonal contraceptives (CHCs) use is becoming an increasingly recognized causes of vestibulodynia.
AIM
This study aims to describe pre- and posttreatment vestibular pain, sex hormone binding globulin (SHBG), and calculated free testosterone levels in women undergoing treatment for vestibulodynia.
METHODS
This was a chart review of 50 premenopausal women who presented with vestibular pain while currently using CHCs. Pre- and posttreatment vestibular pain, SHBG, and calculated free testosterone levels were assessed.
RESULTS
There was a statistically significant improvement in posttreatment vestibular pain scores (P = 0.001), SHBG (P = 0.001), and calculated free testosterone (P = 0.001) levels from baseline.
CONCLUSION
Women with vestibulodynia that began while on CHC may effectively be treated by discontinuing the CHC combined with the application topical hormone therapy. Symptomatic improvement is accompanied by normalization of calculated free testosterone and SHBG values. Burrows LJ and Goldstein AT. The treatment of vestibulodynia with topical estradiol and testosterone. Sex Med 2013;1:30-33.
简介
联合激素避孕药（CHCs）的使用正日益被认为是导致前庭疼痛的原因之一。
目的
本研究旨在描述正在接受前庭疼痛治疗的女性在治疗前后的前庭疼痛、性激素结合球蛋白（SHBG）和计算的游离睾酮水平。
方法
这是对 50 名正在使用 CHC 且出现前庭疼痛的绝经前妇女的图表回顾。评估了治疗前后的前庭疼痛评分、SHBG 和计算的游离睾酮水平。
结果
治疗后的前庭疼痛评分（P = 0.001）、SHBG（P = 0.001）和计算的游离睾酮（P = 0.001）水平均从基线显著改善。
结论
正在使用 CHC 时开始出现前庭疼痛的女性可能通过停止使用 CHC 联合应用局部激素治疗而有效治疗。症状改善伴随着计算的游离睾酮和 SHBG 值的正常化。Burrows LJ 和 Goldstein AT。局部雌二醇和睾酮治疗前庭疼痛。性医学 2013;1:30-33.
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