Peter S, Wolz C, Kaase M, Marschal M, Schulte B, Vogel W, Autenrieth I, Willmann M
Institute of Medical Microbiology and Hygiene, University of Tübingen Tübingen, Germany ; German Centre for Infection Research (DZIF), partner site Tübingen Tübingen, Germany.
National Reference Laboratory for Multidrug Resistant Gram-negative Bacteria, Department of Medical Microbiology, Ruhr University Bochum Bochum, Germany.
New Microbes New Infect. 2014 Mar;2(2):42-5. doi: 10.1002/nmi2.36. Epub 2014 Mar 20.
Metallo-β-lactamases (MBLs) in Enterobacteriaceae are an increasing problem worldwide. This report describes the isolation of Citrobacter freundii carrying IMP-8 MBL from three patients during the period from March 2012 until March 2013 in Germany. The bla IMP-8 enzyme is predominantly found in Asia, where IMP-8 has spread to various enterobacterial species causing serious infections. To our best knowledge, this is the first report of bla IMP-8 habouring Enterobacteriaceae in Europe.
肠杆菌科中的金属β-内酰胺酶（MBLs）在全球范围内是一个日益严重的问题。本报告描述了2012年3月至2013年3月期间在德国从三名患者中分离出携带IMP-8 MBL的弗氏柠檬酸杆菌。bla IMP-8酶主要在亚洲被发现，在那里IMP-8已传播到各种肠杆菌物种，导致严重感染。据我们所知，这是欧洲首次报告携带bla IMP-8的肠杆菌科细菌。
