Systems Neuroscience Group, QIMR Berghofer Medical Research Institute Brisbane, Queensland, Australia ; School of Medicine, Faculty of Medicine and Biomedical Sciences, University of Queensland Queensland, Australia.
Systems Neuroscience Group, QIMR Berghofer Medical Research Institute Brisbane, Queensland, Australia.
Ann Clin Transl Neurol. 2014 Mar;1(3):209-14. doi: 10.1002/acn3.32. Epub 2014 Feb 18.
Burst suppression patterns in the electroencephalogram are a reliable marker of recent severe brain insult. Here we analyze statistical properties of bursts occurring in 20 electroencephalographic recordings acquired from hypothermic asphyxic newborns in the hours immediately following birth. We show that the distributions of burst area and duration in these acute data predict later clinical outcome in both structural neuroimaging and neurodevelopment. Our findings indicate the first early electroencephalographic metrics that offer outcome prediction in asphyxic neonates undergoing hypothermia treatment.
脑电图中的爆发抑制模式是近期严重脑损伤的可靠标志物。在这里，我们分析了在出生后数小时内从低温窒息的新生婴儿中获得的 20 个脑电图记录中发生的爆发的统计特性。我们表明，这些急性数据中爆发面积和持续时间的分布可预测结构神经影像学和神经发育方面的后期临床结果。我们的研究结果表明，在接受低温治疗的窒息新生儿中，首次提供预后预测的早期脑电图指标。
