Hyttel-Sorensen Simon, Hessel Trine Witzner, la Cour Amalia, Greisen Gorm
Department of Neonatology, National University Hospital, Rigshospitalet, Blegdamsvej 9, Copenhagen, DK-2100, Denmark.
Biomed Opt Express. 2014 Sep 18;5(10):3671-83. doi: 10.1364/BOE.5.003671. eCollection 2014 Oct 1.
Previously the NIRS oximeter OxyPrem was calibrated by comparison to the INVOS in a blood-lipid phantom. The aim of the present study was to test this calibration clinically. During vasculur occlusions in 10 adults and after birth in 25 term infants the relationship was OxyPrem = 1.24 x INVOS - 23.6% and OxyPrem = 1.15 x INVOS - 16.2% on the adult arm and infant head, respectively. The precsion during steady state was 4.0% (CI 3.4% to 4.6%) and 3.4% (CI 2.9% to 3.9%) on the arm, and 6.7% (CI 5.9% to 7.6%) and 4.7% (CI 3.5% to 5.9%) on the infant head for OxyPrem and INVOS, respectively. We conclude that the calibration on the blood-lipid phantom was unsuccessful in achieving agreement in clinical measurements.
此前，近红外血氧仪OxyPrem在血液脂质模型中通过与INVOS进行比较来校准。本研究的目的是在临床上测试这种校准。在10名成年人的血管闭塞期间以及25名足月儿出生后，在成人手臂和婴儿头部，两者的关系分别为OxyPrem = 1.24×INVOS - 23.6%和OxyPrem = 1.15×INVOS - 16.2%。在稳态期间，OxyPrem和INVOS在手臂上的精度分别为4.0%（置信区间3.4%至4.6%）和3.4%（置信区间2.9%至3.9%），在婴儿头部分别为6.7%（置信区间5.9%至7.6%）和4.7%（置信区间3.5%至5.9%）。我们得出结论，在血液脂质模型上的校准未能在临床测量中达成一致。
