Kang Tae Wook, Lee Min Woo, Choi Seung Hee, Rhim Hyunchul, Lim Sanghyeok, Song Kyoung Doo, Min Ji Hye, Choi Seo-youn, Lim Hyo Keun, Yang Jehoon
From the *Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University, School of Medicine; and †Animal Laboratory and Research Center, Samsung Biomedical Research Institute, Samsung Medical Center, Seoul, Republic of Korea.
Invest Radiol. 2015 Feb;50(2):81-7. doi: 10.1097/RLI.0000000000000103.
The objective of this study was to compare the targeting and ablation performance between a newly developed radiofrequency (RF) electrode embedded with an electromagnetic position sensor (EMPS) at the electrode tip and a conventional RF electrode.
The institutional animal care and use committee approved this study. The targeting of paint balls within phantoms was performed under ultrasonography guidance by 2 radiologists (beginner vs expert) with an "in-plane" and "out-of-plane" approaches using the new RF electrode and a conventional RF electrode (n = 20 for each method). To evaluate the targeting performance, the electrode placement time and the number of electrode pullbacks for redirection were compared between the 2 electrodes. The ablation performance was also compared by analyzing the ablation volumes in ex vivo bovine and in vivo porcine livers (n = 30 and n = 24, respectively) and the cellular viability of the ablation zone in in vivo specimens.
In the phantom study, the RF electrode embedded with an EMPS showed a significantly shorter electrode placement time compared with the conventional RF electrode in both the in-plane and out-of-plane approaches by both radiologists (P < 0.05). The electrode pullback rate for both radiologists was lower in the new RF electrode than in the conventional RF electrode, but it did not reach statistical significance in the in-plane approach by the expert (P = 0.059). The ablation volumes analyzed with and without cellular viability in the ex vivo and in vivo studies were not significantly different between the 2 electrodes (P > 0.05).
The RF electrode embedded with an EMPS is faster than the conventional electrode in the electrode placement into the target lesions. The ablation performance is not significantly different between the 2 electrodes.
本研究的目的是比较一种新开发的在电极尖端嵌入电磁位置传感器（EMPS）的射频（RF）电极与传统RF电极之间的靶向和消融性能。
该研究获得了机构动物护理和使用委员会的批准。由2名放射科医生（初学者与专家）在超声引导下，采用“平面内”和“平面外”方法，使用新型RF电极和传统RF电极对模拟体中的彩球进行靶向操作（每种方法n = 20）。为了评估靶向性能，比较了两种电极之间的电极放置时间和重新定位时电极回撤的次数。还通过分析离体牛肝和活体猪肝中的消融体积（分别为n = 30和n = 24）以及活体标本中消融区的细胞活力来比较消融性能。
在模拟体研究中，对于两名放射科医生，无论是在“平面内”还是“平面外”方法中，嵌入EMPS的RF电极的电极放置时间均显著短于传统RF电极（P < 0.05）。两名放射科医生使用新型RF电极时的电极回撤率均低于传统RF电极，但在专家进行的“平面内”方法中未达到统计学显著性（P = 0.059）。在离体和活体研究中，分析有无细胞活力情况下的消融体积，两种电极之间无显著差异（P > 0.05）。
嵌入EMPS的RF电极在将电极放置到目标病变中的速度比传统电极更快。两种电极之间的消融性能无显著差异。
