Ge Beihai, Guo Xiaomei
Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Department of Internal Medicine, People's Hospital of Chibi City, Chibi, China.
Int J Stroke. 2015 Feb;10(2):177-84. doi: 10.1111/ijs.12398. Epub 2014 Nov 3.
There is uncertainty about the relationship between sleep duration and stroke risk.
We aimed to clarify the relationship between sleep duration and risk of stroke by using epidemiological evidence.
We searched MEDLINE and EMBASE to identify all studies that might be looking at the association between sleep duration and stroke, including both cohort and cross-sectional studies. Pooled hazard ratios (HRs) and odds ratios (ORs) were calculated through a random-effects model.
Our study included a total of 12 cohort studies and 6 cross-sectional studies. Pooled results from the cohort studies showed that short sleep duration was associated with a higher risk for stroke [HR, 1.13; 95% confidence interval (CI) 1.02-1.25], and that long sleep duration also increases the risk of having a stroke (HR, 1.40; 95% CI, 1.16-1.64). Results from cross-sectional studies confirmed the relationship between stroke and inappropriate sleep duration, either too little sleep or too much. For short sleep duration, the OR was 1.71 (1.39-2.02); for long sleep duration, the OR was 2.12 (1.51-2.73).
Both short and long sleep durations have a significant association with higher risk of stroke.
睡眠时间与中风风险之间的关系尚不确定。
我们旨在通过流行病学证据阐明睡眠时间与中风风险之间的关系。
我们检索了MEDLINE和EMBASE，以识别所有可能研究睡眠时间与中风之间关联的研究，包括队列研究和横断面研究。通过随机效应模型计算合并风险比（HRs）和比值比（ORs）。
我们的研究共纳入了12项队列研究和6项横断面研究。队列研究的合并结果显示，睡眠时间短与中风风险较高相关[HR，1.13；95%置信区间（CI）1.02 - 1.25]，睡眠时间长也会增加中风风险（HR，1.40；95%CI，1.16 - 1.64）。横断面研究结果证实了中风与不适当睡眠时间（睡眠过少或过多）之间的关系。对于睡眠时间短，OR为1.71（1.39 - 2.02）；对于睡眠时间长，OR为2.12（1.51 - 2.73）。
睡眠时间过短和过长均与中风风险较高显著相关。
